Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes
LDJ Bos, LB Ware - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is a common clinical syndrome of acute
respiratory failure as a result of diffuse lung inflammation and oedema. ARDS can be …
respiratory failure as a result of diffuse lung inflammation and oedema. ARDS can be …
Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management
EA Gorman, CM O'Kane, DF McAuley - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …
Ribosome biogenesis in disease: new players and therapeutic targets
L Jiao, Y Liu, XY Yu, X Pan, Y Zhang, J Tu… - … and Targeted Therapy, 2023 - nature.com
The ribosome is a multi-unit complex that translates mRNA into protein. Ribosome
biogenesis is the process that generates ribosomes and plays an essential role in cell …
biogenesis is the process that generates ribosomes and plays an essential role in cell …
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses
J Li, S Deng, J Li, L Li, F Zhang, Y Zou, D Wu… - Cellular & molecular …, 2022 - Springer
Background Acute lung injury (ALI) has received considerable attention in the field of
intensive care as it is associated with a high mortality rate. Obacunone (OB), widely found in …
intensive care as it is associated with a high mortality rate. Obacunone (OB), widely found in …
From ICU syndromes to ICU subphenotypes: consensus report and recommendations for develo** precision medicine in the ICU
Critical care uses syndromic definitions to describe patient groups for clinical practice and
research. There is growing recognition that a “precision medicine” approach is required and …
research. There is growing recognition that a “precision medicine” approach is required and …
Molecular imaging of chemokine-like receptor 1 (CMKLR1) in experimental acute lung injury
PZ Mannes, CE Barnes, J Biermann… - Proceedings of the …, 2023 - National Acad Sciences
The lack of techniques for noninvasive imaging of inflammation has challenged precision
medicine management of acute respiratory distress syndrome (ARDS). Here, we determined …
medicine management of acute respiratory distress syndrome (ARDS). Here, we determined …
Rethinking acute respiratory distress syndrome after COVID-19: if a “better” definition is the answer, what is the question?
VM Ranieri, G Rubenfeld, AS Slutsky - American Journal of …, 2023 - atsjournals.org
The definition of acute respiratory distress syndrome (ARDS) has a somewhat controversial
history, with some even questioning the need for the term “ARDS.” This controversy has …
history, with some even questioning the need for the term “ARDS.” This controversy has …
Personalized medicine using omics approaches in acute respiratory distress syndrome to identify biological phenotypes
In the last decade, research on acute respiratory distress syndrome (ARDS) has made
considerable progress. However, ARDS remains a leading cause of mortality in the …
considerable progress. However, ARDS remains a leading cause of mortality in the …
Neutrophil extracellular traps trigger alveolar epithelial cell necroptosis through the cGAS-STING pathway during acute lung injury in mice
HX Sha, YB Liu, YL Qiu, WJ Zhong… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Extensive loss of alveolar epithelial cells (AECs) undergoing necroptosis is a crucial
mechanism of acute lung injury (ALI), but its triggering mechanism needs to be thoroughly …
mechanism of acute lung injury (ALI), but its triggering mechanism needs to be thoroughly …
A bibliometric analysis of autophagy in lung diseases from 2012 to 2021
F Lin, Y Chen, W Mo, H Zhou, Z **ao, S Hu… - Frontiers in …, 2022 - frontiersin.org
Background Autophagy refers to the process in which cells wrap their damaged organelles
or unwanted proteins into a double-membrane structure and direct them to lysosomes for …
or unwanted proteins into a double-membrane structure and direct them to lysosomes for …