Mammalian skeletal muscle comprises different fiber types, whose identity is first established
during embryonic development by intrinsic myogenic control mechanisms and is later …

The adhesive interactions of cells with their environment through the integrin family of
transmembrane receptors have key roles in regulating multiple aspects of cellular …

Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium
not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a …

Dilated cardiomyopathy is characterised by left ventricular dilation that is associated with
systolic dysfunction. Diastolic dysfunction and impaired right ventricular function can …

First described 15 years ago as a cysteine-rich sequence that was common to a small group
of homeodomain transcription factors, the LIM domain is now recognized as a tandem zinc …

Muscle cells are designed to generate force and movement. There are three types of
mammalian muscles—skeletal, cardiac, and smooth. Skeletal muscles are attached to …

Cardiac and skeletal striated muscles are intricately designed machines responsible for
muscle contraction. Coordination of the basic contractile unit, the sarcomere, and the …

Muscle cells respond to mechanical stretch stimuli by triggering downstream signals for
myocyte growth and survival. The molecular components of the muscle stretch sensor are …

Mechanisms controlling vascular smooth muscle cell (VSMC) plasticity and renewal still
remain to be elucidated completely. A class of small RNAs called microRNAs (miRs) …

▪ Abstract Striated muscle is an intricate, efficient, and precise machine that contains
complex interconnected cytoskeletal networks critical for its contractile activity. The …