This article addresses the bioactive components in coffee aroma, their metabolism, and the
mechanism of action in lowering the risk of various potential health problems. The main …

Obesity is a risk factor that leads to the development of other diseases such as dyslipidemia
and diabetes. These three metabolic disorders can occur simultaneously, hence, the …

Kahweol and cafestol are two diterpenes extracted from Coffea arabica beans that have
distinct biological activities. Recent research describes their potential activities, which …

Atherosclerosis, a major cause of cardiovascular diseases, is influenced by modifiable
factors such as adiposity and blood cholesterol. Diet is crucial in these areas, particularly …

Twelve 3, 5-disubstituted-thiazolidine-2, 4-dione (TZD) hybrids were synthesized using
solution phase chemistry. Continuing our previous work, nine O-modified ethyl vanillin (8a–i) …

Several plant secondary metabolites are used in the production of different pharmaceuticals
based on their biological activities. The conservation and sustainable use of medicinal …

Type 1 diabetes stem-cell-based therapy is one of the best therapeutic approaches for
pancreatic damage treatment due to stem cell tissue regeneration. Epigallocatechin gallate …

Oxysterol 7α-hydroxylase (CYP7B1) controls the levels of intracellular regulatory oxysterols
generated by the “acidic pathway” of cholesterol metabolism. Previously, we demonstrated …

Caffeine is one of the predominant dietary components and psychostimulants present in
coffee, a widely appreciated beverage. Corroborating epidemiological and laboratory …

Rosmarinic acid (RA), a natural ester phenolic compound, is known to have antioxidant and
anti-inflammatory properties. RA has also been reported to exhibit a hypoglycemic effect; …