Synthesis of heterocycles via electrophilic cyclization of alkynes containing heteroatom
The interest in synthesizing heterocycles has always been enormous. The literature contains
a variety of synthetic approaches to the heterocycle ring structures, much of which has been …
a variety of synthetic approaches to the heterocycle ring structures, much of which has been …
[HTML][HTML] Quinoline: A versatile heterocyclic
A Marella, OP Tanwar, R Saha, MR Ali… - Saudi Pharmaceutical …, 2013 - Elsevier
Quinoline or 1-aza-naphthalene is a weak tertiary base. Quinoline ring has been found to
possess antimalarial, anti-bacterial, antifungal, anthelmintic, cardiotonic, anticonvulsant, anti …
possess antimalarial, anti-bacterial, antifungal, anthelmintic, cardiotonic, anticonvulsant, anti …
Current scenario of drug development for leishmaniasis.
SL Croft, K Seifert, V Yardley - The Indian journal of …, 2006 - researchonline.lshtm.ac.uk
Although three new drugs or drug formulations, liposomal amphotericin B (AmBisome),
miltefosine and paromomycin should be available for the treatment of visceral leishmaniasis …
miltefosine and paromomycin should be available for the treatment of visceral leishmaniasis …
Direct synthesis of pyridines and quinolines by coupling of γ-amino-alcohols with secondary alcohols liberating H 2 catalyzed by ruthenium pincer complexes
A novel, one-step synthesis of substituted pyridine-and quinoline-derivatives was achieved
by acceptorless dehydrogenative coupling of γ-aminoalcohols with secondary alcohols. The …
by acceptorless dehydrogenative coupling of γ-aminoalcohols with secondary alcohols. The …
Synthesis and antiprotozoal activity of some new synthetic substituted quinoxalines
X Hui, J Desrivot, C Bories, PM Loiseau… - Bioorganic & medicinal …, 2006 - Elsevier
A series of 29 new quinoxalines was synthesized and evaluated in vitro against several
parasites (Leishmania donovani, Trypanosoma brucei brucei, and Trichomonas vaginalis) …
parasites (Leishmania donovani, Trypanosoma brucei brucei, and Trichomonas vaginalis) …
Synthesis, leishmanicidal, trypanocidal and cytotoxic activities of quinoline-chalcone and quinoline-chromone hybrids
JC Coa, E García, M Carda, R Agut, ID Vélez… - Medicinal Chemistry …, 2017 - Springer
We report herein the synthesis and biological activities (cytotoxicity, leishmanicidal and
trypanocidal) of six quinoline-chalcone and five quinoline-chromone hybrids. The …
trypanocidal) of six quinoline-chalcone and five quinoline-chromone hybrids. The …
A review on synthetic investigation for quinoline-recent green approaches
Quinolines are a prominent heterocyclic motif and crucial building blocks in creating
physiologically active compounds. Due to the fast development of novel medicines with a …
physiologically active compounds. Due to the fast development of novel medicines with a …
[HTML][HTML] Synthesis and antioxidant properties of novel quinoline–chalcogenium compounds
L Savegnago, AI Vieira, N Seus, BS Goldani… - Tetrahedron …, 2013 - Elsevier
Herein we describe our results on the synthesis and antioxidant properties of 4-
arylchalcogenyl-7-chloroquinolines. This new class of compounds has been synthesized in …
arylchalcogenyl-7-chloroquinolines. This new class of compounds has been synthesized in …
A catalyst-free benzylic C–H bond olefination of azaarenes for direct Mannich-like reactions
Y Yan, K Xu, Y Fang, Z Wang - The Journal of Organic Chemistry, 2011 - ACS Publications
A highly efficient synthesis of trans-alkenylazaarene under catalyst-free conditions was
developed via the addition of methylazaarenes to N-sulfonyl aldimines and a subsequent C …
developed via the addition of methylazaarenes to N-sulfonyl aldimines and a subsequent C …
One pot efficient diversity oriented synthesis of polyfunctional styryl thiazolopyrimidines and their bio-evaluation as antimalarial and anti-HIV agents
S Fatima, A Sharma, R Saxena, R Tripathi… - European journal of …, 2012 - Elsevier
An efficient one pot synthesis of a series of pluripotent (E)-1-(3-methyl-5-aryl-7-styryl-5H-
thiazolo [3, 2-a] pyrimidin-6-yl)-3-arylprop-2-en-1-ones is reported. It involves reaction of 5 …
thiazolo [3, 2-a] pyrimidin-6-yl)-3-arylprop-2-en-1-ones is reported. It involves reaction of 5 …