Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

The failure of chemotherapy is a major challenge nowadays, and in order to ensure effective
treatment of cancer patients, it is of great importance to reveal the molecular pathways and …

Although cisplatin is an effective anticancer drug, its clinical application is limited due to
various side effects, especially nephrotoxicity. In this study, we investigated the protective …

Lotus is a member of a small family of Nelumbonaceae and is regarded as a sacred flower
grown as a freshwater aquatic plant. All plant parts are utilized as food and medicine. Lotus …

Simple Summary The plant Nelumbo nucifera (Gaertn.), commonly known as lotus, sacred
lotus, Indian lotus, water lily, or Chinese water lily, is an aquatic perennial crop belonging to …

Cisplatin-based chemotherapeutic regimens are the most frequently used adjuvant
treatments for many types of cancer. However, the development of chemoresistance to …

Triple-negative breast cancer (TNBC), defined as loss of estrogen, progesterone, and Her2
receptors, is a subtype of highly aggressive breast cancer with worse prognosis and poor …

This article recapitulates the existing in vitro and in vivo studies focusing on the effects of
neferine-an alkaloid derivative of lotus plant, in various disease models and its effects on …

Drug resistance is still an obstacle in cancer therapy, leading to the failure of tumor
treatment. The emergence of tumor drug resistance has always been a main concern of …

Abstract Ethnopharmacological relevance Plumula Nelumbinis, the green embryo of the
mature seeds of Nelumbo nucifera Gaertn, has a medical history of over 400 years. It is …