Rural communities in develo** countries lack access to affordable, reliable, and
sustainable forms of energy, which are essential factors for improving living conditions …

3′-untranslated regions (3′-UTRs) are the noncoding parts of mRNAs. Compared to
yeast, in humans, median 3′-UTR length has expanded approximately tenfold alongside …

In recent years translation elongation has emerged as an important contributor to the
regulation of gene expression. There are multiple quality control checkpoints along the way …

The biophysical rules that govern folding of small, single‐domain proteins in dilute solutions
are now quite well understood. The mechanisms underlying co‐translational folding of …

The faithful assembly of protein complexes in space and time is a hallmark of cellular
homeostasis. Complex assembly might be seeded already during translation, if interacting …

The assembly of heteromeric protein complexes is an inherently stochastic process in which
multiple genes are expressed separately into proteins, which must then somehow find each …

The MYC oncogene is upregulated in human cancers by translocation, amplification, and
mutation of cellular pathways that regulate Myc. Myc/Max heterodimers bind to E box …

Gillespie syndrome (GS) is characterized by bilateral iris hypoplasia, congenital hypotonia,
non-progressive ataxia, and progressive cerebellar atrophy. Trio-based exome sequencing …

Highlights•Cotranslational assembly of protein complexes is a widespread phenomenon.•
Cotranslational assembly can occur via cis-or trans-acting mechanisms.•Operons facilitate …

Approximately half of proteins with experimentally determined structures can interact with
other copies of themselves and assemble into homomeric complexes, the overwhelming …