Local drug delivery strategies towards wound healing

R Tiwari, K Pathak - Pharmaceutics, 2023 - mdpi.com
A particular biological process known as wound healing is connected to the overall
phenomena of growth and tissue regeneration. Several cellular and matrix elements work …

The potential of MSC-based cell-free therapy in wound healing—a thorough literature review

H Ma, WS Siu, PC Leung - International Journal of Molecular Sciences, 2023 - mdpi.com
A wound is an interruption of the normal anatomic structure and function of the skin, which is
critical in protecting against foreign pathogens, regulating body temperature and water …

[HTML][HTML] Double hits with bioactive nanozyme based on cobalt-doped nanoglass for acute and diabetic wound therapies through anti-inflammatory and pro-angiogenic …

N Mandakhbayar, YS Ji, A El-Fiqi, KD Patel, DS Yoon… - Bioactive Materials, 2024 - Elsevier
Regeneration of pathological wounds, such as diabetic ulcers, poses a significant challenge
in clinical settings, despite the widespread use of drugs. To overcome clinical side effects …

[HTML][HTML] 3D-printed placental-derived bioinks for skin tissue regeneration with improved angiogenesis and wound healing properties

Z Bashiri, MR Fomeshi, HG Hamidabadi, D Jafari… - Materials Today Bio, 2023 - Elsevier
Extracellular matrix (ECM)-based bioinks has attracted much attention in recent years for 3D
printing of native-like tissue constructs. Due to organ unavailability, human placental ECM …

Exosomes derived from human amniotic mesenchymal stem cells facilitate diabetic wound healing by angiogenesis and enrich multiple lncRNAs

S Fu, H Zhang, X Li, Q Zhang, C Guo, K Qiu… - Tissue Engineering and …, 2023 - Springer
Background: Diabetic wound healing remains a major challenge due to the impaired
functionality of angiogenesis by persistent hyperglycemia. Mesenchymal stem cell …

Skin precursor‐derived Schwann cells accelerate in vivo prevascularization of tissue‐engineered nerves to promote peripheral nerve regeneration

M Li, X Cheng, S Feng, H Zhu, P Lu, P Zhang, X Cai… - Glia, 2023 - Wiley Online Library
Prevascularization strategies have become a hot spot in tissue engineering. As one of the
potential candidates for seed cells, skin precursor‐derived Schwann cells (SKP‐SCs) were …

Mesenchymal stem cells-based drug delivery systems for diabetic foot ulcer: A review

HM Zhang, ML Yang, JZ **, GY Yang… - World Journal of …, 2023 - pmc.ncbi.nlm.nih.gov
The complication of diabetes, which is known as diabetic foot ulcer (DFU), is a significant
concern due to its association with high rates of disability and mortality. It not only severely …

Fibrin-Based Hydrogels with Reactive Amphiphilic Copolymers for Mechanical Adjustments Allow for Capillary Formation in 2D and 3D Environments

S Wein, C Schemmer, MA Al Enezy-Ulbrich, SA Jung… - Gels, 2024 - mdpi.com
This study focuses on enhancing controllable fibrin-based hydrogels for tissue engineering,
addressing existing weaknesses. By integrating a novel copolymer, we improved the …

[HTML][HTML] Engineered Vesicles and Hydrogel Technologies for Myocardial Regeneration

K Ghassemi, K Inouye, T Takhmazyan, V Bonavida… - Gels, 2023 - mdpi.com
Increased prevalence of cardiovascular disease and potentially life-threatening
complications of myocardial infarction (MI) has led to emerging therapeutic approaches …