Penetration enhancers
AC Williams, BW Barry - Advanced drug delivery reviews, 2012 - Elsevier
One long-standing approach for improving transdermal drug delivery uses penetration
enhancers (also called sorption promoters or accelerants) which penetrate into skin to …
enhancers (also called sorption promoters or accelerants) which penetrate into skin to …
Microemulsions as transdermal drug delivery vehicles
A Kogan, N Garti - Advances in colloid and interface science, 2006 - Elsevier
Microemulsions are clear, stable, isotropic mixtures of oil, water, and surfactant, frequently in
combination with a cosurfactant. Microemulsions have been intensively studied during the …
combination with a cosurfactant. Microemulsions have been intensively studied during the …
Safety evaluation of topical applications of ethanol on the skin and inside the oral cavity
DW Lachenmeier - Journal of Occupational Medicine and Toxicology, 2008 - Springer
Ethanol is widely used in all kinds of products with direct exposure to the human skin (eg
medicinal products like hand disinfectants in occupational settings, cosmetics like hairsprays …
medicinal products like hand disinfectants in occupational settings, cosmetics like hairsprays …
Quantitative structure–permeability relationships (QSPRs) for percutaneous absorption
GP Moss, JC Dearden, H Patel, MTD Cronin - Toxicology in vitro, 2002 - Elsevier
Quantitative structure–permeability relationships (QSPRs) have been derived by many
researchers to model the passive, diffusion-controlled, percutaneous penetration of …
researchers to model the passive, diffusion-controlled, percutaneous penetration of …
Synergistic penetration enhancement effect of ethanol and phospholipids on the topical delivery of cyclosporin A
DD Verma, A Fahr - Journal of controlled release, 2004 - Elsevier
In the present study, ethanol was used with a commercially available lipid mixture, NAT
8539, to improve the topical delivery of cyclosporin A (CyA). The vesicles formed from this …
8539, to improve the topical delivery of cyclosporin A (CyA). The vesicles formed from this …
Skin delivery of 5‐fluorouracil from ultradeformable and standard liposomes in‐vitro
The potential use of ultradeformable and standard liposomes as skin drug delivery systems
was investigated in‐vitro. An improved experimental design gave a good measure for skin …
was investigated in‐vitro. An improved experimental design gave a good measure for skin …
Tacrolimus-loaded ethosomes: physicochemical characterization and in vivo evaluation
G Li, Y Fan, C Fan, X Li, X Wang, M Li, Y Liu - European journal of …, 2012 - Elsevier
The purpose of this work was to prepare and characterize a novel ethosomal carrier for
tacrolimus, an immunosuppressant treating atopic dermatitis (AD), and to investigate …
tacrolimus, an immunosuppressant treating atopic dermatitis (AD), and to investigate …
Microemulsions as a surrogate carrier for dermal drug delivery
Microemulsions are isotropic, thermodynamically stable transparent (or translucent) systems
of oil, water, and surfactant, frequently in combination with a cosurfactant with a droplet size …
of oil, water, and surfactant, frequently in combination with a cosurfactant with a droplet size …
Innovative strategies for enhancing topical and transdermal drug delivery
DIJ Morrow, PA McCarron, AD Woolfson… - The Open Drug …, 2007 - benthamopen.com
Historically, the skin was thought to be a simple homogenous barrier. However, it is now
known to be a highly specialised organ, and plays a key role in homeostasis. The protective …
known to be a highly specialised organ, and plays a key role in homeostasis. The protective …
Oestradiol permeation through human skin and silastic membrane: effects of propylene glycol and supersaturation
NA Megrab, AC Williams, BW Barry - Journal of controlled release, 1995 - Elsevier
One approach to transdermal permeation enhancement investigated in this paper is to
increase the thermodynamic activity of a drug in the transdermal delivery system to …
increase the thermodynamic activity of a drug in the transdermal delivery system to …