Medicinal plants have historically proven their value as a source of molecules with
therapeutic potential, and nowadays still represent an important pool for the identification of …

Geometrical E→ Z alkene isomerization is intimately entwined in the historical fabric of
organic photochemistry and is enjoying a renaissance (Roth et al. Angew. Chem., Int. Ed …

The use of photochemical transformations is a powerful strategy that allows for the formation
of a high degree of molecular complexity from relatively simple building blocks in a single …

Atomic clusters, consisting of a few to a few thousand atoms, have emerged over the past 40
years as the ultimate nanoparticles, whose structure and properties can be controlled one …

The therapeutic areas of infectious diseases and oncology have benefited from abundant
scaffold diversity in natural products, able to interact with many specific targets within the cell …

Owing to the high diversity of terrestrial and marine organisms, natural products (secondary
metabolites) are some of the most successful source of drug leads for the treatment of many …

Natural products (NPs) are secondary metabolites produced and used by organisms for
defending or adapting purposes. These molecules were naturally selected during thousands …

The drug market is still dominated by small molecules, and more than 80% of the clinical
development of drug candidates in the top 20 pharmaceutical firms is still based on small …

Organic compounds from terrestrial and marine organisms have extensive past and present
use in the treatment of many diseases and serve as compounds of interest both in their …

Covering: 2005 to 2007 Natural product and natural product-derived compounds that are
being evaluated in clinical trials or are in registration (as at 31st December 2007) have been …