Basal forebrain cholinergic circuits and signaling in cognition and cognitive decline
Recent work continues to place cholinergic circuits at center stage for normal executive and
mnemonic functioning and provides compelling evidence that the loss of cholinergic …
mnemonic functioning and provides compelling evidence that the loss of cholinergic …
The cholinergic system in aging and neuronal degeneration
R Schliebs, T Arendt - Behavioural brain research, 2011 - Elsevier
The basal forebrain cholinergic complex comprising medial septum, horizontal and vertical
diagonal band of Broca, and nucleus basalis of Meynert provides the mayor cholinergic …
diagonal band of Broca, and nucleus basalis of Meynert provides the mayor cholinergic …
Alzheimer's disease and the basal forebrain cholinergic system: relations to β-amyloid peptides, cognition, and treatment strategies
Alzheimer's disease (AD) is the most common form of degenerative dementia and is
characterized by progressive impairment in cognitive function during mid-to late-adult life …
characterized by progressive impairment in cognitive function during mid-to late-adult life …
On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis
RT Bartus - Experimental neurology, 2000 - Elsevier
Life's Journey If life is indeed a journey, then poetry must be the map that reveals all its
topographic possibilities… while science is the compass that keeps us from getting lost.—RT …
topographic possibilities… while science is the compass that keeps us from getting lost.—RT …
Neuronal nicotinic receptors in the human brain
D Paterson, A Nordberg - Progress in neurobiology, 2000 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand gated ion
channels which are widely distributed in the human brain. Multiple subtypes of these …
channels which are widely distributed in the human brain. Multiple subtypes of these …
DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers
CF Lippa, JE Duda, M Grossman, HI Hurtig… - Neurology, 2007 - AAN Enterprises
For more than a decade, researchers have refined criteria for the diagnosis of dementia with
Lewy bodies (DLB) and at the same time have recognized that cognitive impairment and …
Lewy bodies (DLB) and at the same time have recognized that cognitive impairment and …
Nicotinic acetylcholine receptors: from structure to brain function
RC Hogg, M Raggenbass, D Bertrand - Reviews of physiology …, 2003 - Springer
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels and can be
divided into two groups: muscle receptors, which are found at the skeletal neuromuscular …
divided into two groups: muscle receptors, which are found at the skeletal neuromuscular …
[HTML][HTML] Nicotinic acetylcholine receptors in neurological and psychiatric diseases
AV Terry Jr, K Jones, D Bertrand - Pharmacological Research, 2023 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that are
widely distributed both pre-and post-synaptically in the mammalian brain. By modulating …
widely distributed both pre-and post-synaptically in the mammalian brain. By modulating …
Galantamine: a review of its use in Alzheimer's disease
LJ Scott, KL Goa - Drugs, 2000 - Springer
Currently, acetylcholinesterase (AChE) inhibitors are the most promising class of drugs for
the treatment of Alzheimer's disease (AD). Galantamine is a reversible, competitive, tertiary …
the treatment of Alzheimer's disease (AD). Galantamine is a reversible, competitive, tertiary …
β-Amyloid activates the mitogen-activated protein kinase cascade via hippocampal α7 nicotinic acetylcholine receptors: in vitro and in vivo mechanisms related to …
KT Dineley, M Westerman, D Bui, K Bell… - Journal of …, 2001 - Soc Neuroscience
Alzheimer's Disease (AD) is the most common of the senile dementias, the prevalence of
which is increasing rapidly, with a projected 14 million affected worldwide by 2025. The …
which is increasing rapidly, with a projected 14 million affected worldwide by 2025. The …