Pathology and MRI: exploring cognitive impairment in MS

F Paul - Acta Neurologica Scandinavica, 2016 - Wiley Online Library
Cognitive impairment is a frequent symptom in people with multiple sclerosis, affecting up to
70% of patients. This article reviews the published association of cognitive dysfunction with …

Clinical and research MRI techniques for assessing spinal cord integrity in degenerative cervical myelopathy—a sco** review

B He, K Sheldrick, A Das, A Diwan - Biomedicines, 2022 - mdpi.com
Background: Degenerative cervical myelopathy (DCM) manifests as the primary cause of
spinal cord dysfunction and is non-traumatic, chronic and progressive in nature …

Deep grey matter injury in multiple sclerosis: a NAIMS consensus statement

D Ontaneda, PC Raza, KR Mahajan, DL Arnold… - 2021 - academic.oup.com
Although multiple sclerosis has traditionally been considered a white matter disease,
extensive research documents the presence and importance of grey matter injury including …

Neuroimaging correlates of cognitive dysfunction in adults with multiple sclerosis

M Petracca, G Pontillo, M Moccia, A Carotenuto… - Brain Sciences, 2021 - mdpi.com
Cognitive impairment is a frequent and meaningful symptom in multiple sclerosis (MS),
caused by the accrual of brain structural damage only partially counteracted by effective …

Lower myelin content is associated with more rapid cognitive decline among cognitively unimpaired individuals

Z Gong, M Bilgel, M Kiely, C Triebswetter… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction The influence of myelination on longitudinal changes in cognitive performance
remains unclear. Methods For each participant (N= 123), longitudinal cognitive scores were …

Quantitative T1 brain map** in early relapsing-remitting multiple sclerosis: longitudinal changes, lesion heterogeneity and disability

JG Harper, EN York, R Meijboom, A Kampaite… - European …, 2024 - Springer
Objectives To quantify brain microstructural changes in recently diagnosed relapsing-
remitting multiple sclerosis (RRMS) using longitudinal T 1 measures, and determine their …

[HTML][HTML] MAGNIMS recommendations for harmonization of MRI data in MS multicenter studies

N De Stefano, M Battaglini, D Pareto, R Cortese… - NeuroImage: Clinical, 2022 - Elsevier
There is an increasing need of sharing harmonized data from large, cooperative studies as
this is essential to develop new diagnostic and prognostic biomarkers. In the field of multiple …

Heterogeneous pathological processes account for thalamic degeneration in multiple sclerosis: insights from 7 T imaging

C Louapre, ST Govindarajan, C Giannì… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: Thalamic degeneration impacts multiple sclerosis (MS) prognosis. Objective:
To investigate heterogeneous thalamic pathology, its correlation with white matter (WM) …

Gray matter integrity predicts white matter network reorganization in multiple sclerosis

A Radetz, N Koirala, J Krämer, A Johnen… - Human brain …, 2020 - Wiley Online Library
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease leading to
gray matter atrophy and brain network reconfiguration as a response to increasing tissue …

T1 relaxation times in the cortex and thalamus are associated with working memory and information processing speed in patients with multiple sclerosis

C Thaler, I Hartramph, JP Stellmann, C Heesen… - Frontiers in …, 2021 - frontiersin.org
Background: Cortical and thalamic pathologies have been associated with cognitive
impairment in patients with multiple sclerosis (MS). Objective: We aimed to quantify cortical …