Mitochondria serve a crucial role in cell growth and proliferation by supporting both ATP
synthesis and the production of macromolecular precursors. Whereas oxidative …

Progeroid disorders make up a heterogeneous group of very rare hereditary diseases
characterized by clinical signs that often mimic physiological aging in a premature manner …

Mitogen-activated protein kinase kinases (MAPKKs) play a critical role in the mitogen-
activated protein kinase (MAPK) signaling pathway, transducing external stimuli into …

Alzheimer's disease (AD) is an age-related neurodegenerative disorder (NDD). In the
central nervous system (CNS), immune cells like microglia could reprogram intracellular …

The bifunctional enzyme Δ 1-pyrroline-5-carboxylate synthase (P5CS) is vital to the
synthesis of proline and ornithine, playing an essential role in human health and agriculture …

Abstract Background Chrysanthemum Fusarium wilt is a common fungal disease caused by
Fusarium oxysporum, which causes continuous crop** obstacles and huge losses to the …

Division of labour: mitochondria split to meet energy demands Skip to main content Thank you
for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

The first and committed step in proline synthesis from glutamate is catalyzed by δ1‐pyrroline‐
5‐carboxylate synthetase (P5CS). Two P5CS genes have been found in most angiosperms …

Enterocytozoon hepatopenaei (EHP) is a specialized intracellular parasite that mainly
resides in the hepatopancreas of shrimp, causing significant growth retardation in shrimp. In …

The pathway for synthesis of proline in most forms of life produces a highly unstable
intermediate, γ-L-glutamyl 5-phosphate (GP). For nearly 70 y, channeling of this …