Fluoride is ubiquitously present throughout the world. It is released from minerals, magmatic
gas, and industrial processing, and travels in the atmosphere and water. Exposure to low …

The small GTP-binding protein ADP ribosylation factor (ARF) regulates, through a GTP
cycle, the reversible binding of cytosolic coat proteins to Golgi membranes. By determining …

ADP-ribosylation factor (ARF) 6 localizes to the plasma membrane (PM) in its GTP state and
to a tubulovesicular compartment in its GDP state in HeLa cells that express wild-type or …

COPI and COPII are vesicle coat complexes whose assembly is regulated by the ARF1 and
Sar1 GTPases, respectively. We show that COPI and COPII coat complexes are recruited …

We have developed an assay to monitor the assembly of the COPII coat onto liposomes in
real time. We show that with Sar1pGTP bound to liposomes, a single round of assembly and …

Protein coats deform flat lipid membranes into buds and capture membrane proteins to form
transport vesicles,,. The assembly/disassembly cycle of the COPI coat on Golgi membranes …

The ARF6 GTPase regulates a novel endosomal-plasma membrane recycling pathway and
influences cortical actin remodeling. Here we examined the relationship between ARF6 and …

Small GTP-binding proteins such as ADP-ribosylation factor 1 (ARF1) and Sar1p regulate
the membrane association of coat proteins involved in intracellular membrane trafficking …

Formation of coatomer-coated vesicles from Golgi-enriched membranes requires the
activation of a small GTP-binding protein, ADP ribosylation factor (ARF). ARF is also an …

To study the effector function of the ADP-ribosylation factor (ARF) 6 GTP-binding protein, we
transfected HeLa cells with wild-type, epitope-tagged ARF6. Previously shown to indirectly …