Abstract Structure‐based ligand design in medicinal chemistry and crop protection relies on
the identification and quantification of weak noncovalent interactions and understanding the …

Cryptosporidium is a protozoan parasite of medical and veterinary importance that causes
gastroenteritis in a variety of vertebrate hosts. Several studies have reported different …

Mechanisms of action (MoAs) have been elusive for most antimalarial drugs in clinical use.
Decreasing responsiveness to antimalarial treatments stresses the need for a better …

Cysteine proteases (CPs) play key roles in the pathogenesis of protozoan parasites,
including cell/tissue penetration, hydrolysis of host or parasite proteins, autophagy, and …

Cysteine proteases play numerous indispensable roles in the biology of parasitic organisms.
Aside from previously known general catabolic functions and protein processing, cysteine …

Continued and sustainable improvements in antimalarial medicines through focused
research and development are essential for the world's future ability to treat and control …

Many natural products and derivatives thereof belong to the standard repertoire of cancer
chemotherapy. Examples are Vinca alkaloids, taxanes and camptothecins. In recent years …