Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …

Metabolic syndrome (MetS), which is characterized by insulin resistance, high blood
glucose, obesity, and dyslipidemia, is known to increase the risk of dementia accompanied …

Objective To determine whether dietary interventions that increase n-3 fatty acids with and
without reduction in n-6 linoleic acid can alter circulating lipid mediators implicated in …

Pain is one of the main problems for modern society and medicine, being the most common
symptom described by almost all patients. When pain becomes chronic, the life of the …

Octadecanoids are broadly defined as oxylipins (ie, lipid mediators) derived from 18-carbon
fatty acids. In contrast to the well-studied eicosanoids, there is a lack of analytical methods …

Fatty acids (FAs) are essential components of the central nervous system (CNS), where they
exert multiple roles in health and disease. Among the FAs, docosahexaenoic acid (DHA) …

Increased intake of omega-6 rich plant oils such as soybean and corn oil over the past few
decades has inadvertently tripled the amount of n-6 linoleic acid (LA, 18: 2n-6) in the diet …

Oxylipins are enzymatic and non-enzymatic metabolites of mono-or polyunsaturated fatty
acids that encompass potent lipid mediators including the eicosanoids and docosanoids …

Abstract Background The standard Western diet is high in processed hyperpalatable foods
that displace nutrient-dense whole foods, leading to inflammation and oxidative stress …

Chronic pain is the leading cause of disability worldwide and is commonly associated with
comorbid disorders. However, the role of diet in chronic pain is poorly understood. Of …