The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens

R Wyatt, J Sodroski - Science, 1998‏ - science.org
The human immunodeficiency virus–type 1 (HIV-1) envelope glycoproteins interact with
receptors on the target cell and mediate virus entry by fusing the viral and cell membranes …

Pathogenesis of human immunodeficiency virus infection

JA Levy - Microbiological reviews, 1993‏ - journals.asm.org
The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and esca** the host immune response against it. HIV …

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5

L Wu, NP Gerard, R Wyatt, H Choe, C Parolin… - Nature, 1996‏ - nature.com
FOR efficient entry into target cells, primary macrophage-tropic and laboratory-adapted
human immunodeficiency viruses type 1 (HIV-1) require particular chemokine receptors …

[كتاب][B] HIV and the pathogenesis of AIDS.

JA Levy - 1994‏ - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation

MS Diamond, DE Staunton, SD Marlin, TA Springer - Cell, 1991‏ - cell.com
Both the integrins LFA-1 and Mac-l bind to ICAM-1, an immunoglobulin superfamily member.
Previously, we localized the binding sites of LFA-1 and the major group of human …

Dissociation of gp120 from HIV-1 virions induced by soluble CD4

JP Moore, JA McKeating, RA Weiss, QJ Sattentau - Science, 1990‏ - science.org
The CD4 antigen is the high affinity cellular receptor for the human immunodeficiency virus
type-1 (HIV-1). Binding of recombinant soluble CD4 (sCD4) or the purified V1 domain of …

The integrin α4β7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1

C Cicala, E Martinelli, JP McNally, DJ Goode… - Proceedings of the …, 2009‏ - pnas.org
Both activated and resting CD4+ T cells in mucosal tissues play important roles in the
earliest phases of infection after sexual transmission of HIV-1, a process that is inefficient …

Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding.

QJ Sattentau, JP Moore - The Journal of experimental medicine, 1991‏ - rupress.org
The human immunodeficiency virus (HIV) binds to the surface of T lymphocytes and other
cells of the immune system via a high affinity interaction between CD4 and the HIV outer …

[18] Systematic mutational analyses of protein-protein interfaces

JA Wells - Methods in enzymology, 1991‏ - Elsevier
Publisher Summary This chapter presents the systematic mutational analyses of protein–
protein interfaces. Mutational analysis is a powerful approach for identifying protein–protein …

A functional map of HIV-host interactions in primary human T cells

J Hiatt, JF Hultquist, MJ McGregor… - Nature …, 2022‏ - nature.com
Abstract Human Immunodeficiency Virus (HIV) relies on host molecular machinery for
replication. Systematic attempts to genetically or biochemically define these host factors …