Paternal impact on the life course development of obesity and type 2 diabetes in the offspring
GC Sharp, DA Lawlor - Diabetologia, 2019 - Springer
The aetiologies of obesity and type 2 diabetes are incredibly complex, but the potential role
of paternal influences remains relatively understudied. A better understanding of paternal …
of paternal influences remains relatively understudied. A better understanding of paternal …
Non-linear mendelian randomization: detection of biases using negative controls with a focus on BMI, vitamin D and ldl cholesterol
Mendelian randomisation (MR) is an established technique in epidemiological investigation,
using the principle of random allocation of genetic variants at conception to estimate the …
using the principle of random allocation of genetic variants at conception to estimate the …
Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income
Socioeconomic position (SEP) is a multi-dimensional construct reflecting (and influencing)
multiple socio-cultural, physical, and environmental factors. In a sample of 286,301 …
multiple socio-cultural, physical, and environmental factors. In a sample of 286,301 …
Reflection on modern methods: five myths about measurement error in epidemiological research
M Van Smeden, TL Lash… - International journal of …, 2020 - academic.oup.com
Epidemiologists are often confronted with datasets to analyse which contain measurement
error due to, for instance, mistaken data entries, inaccurate recordings and measurement …
error due to, for instance, mistaken data entries, inaccurate recordings and measurement …
[HTML][HTML] Advances in methodologies of negative controls: a sco** review
Objective Negative control is considered an important tool to mitigate biases in
observational studies. The aim of this sco** review was to summarize current …
observational studies. The aim of this sco** review was to summarize current …
Prevention of coronavirus disease 2019 among older adults receiving pneumococcal conjugate vaccine suggests interactions between Streptococcus pneumoniae …
Background While secondary pneumococcal pneumonia occurs less commonly after
coronavirus disease 2019 (COVID-19) than after other viral infections, it remains unclear …
coronavirus disease 2019 (COVID-19) than after other viral infections, it remains unclear …
Associations of maternal quitting, reducing, and continuing smoking during pregnancy with longitudinal fetal growth: Findings from Mendelian randomization and …
JS Brand, R Gaillard, J West, RRC McEachan… - PLoS …, 2019 - journals.plos.org
Background Maternal smoking during pregnancy is an established risk factor for low infant
birth weight, but evidence on critical exposure windows and timing of fetal growth restriction …
birth weight, but evidence on critical exposure windows and timing of fetal growth restriction …
The use of negative control outcomes in Mendelian randomization to detect potential population stratification
A key assumption of Mendelian randomization (MR) analysis is that there is no association
between the genetic variants used as instruments and the outcome other than through the …
between the genetic variants used as instruments and the outcome other than through the …
Sodium‐glucose co‐transporter‐2 inhibitors and susceptibility to COVID‐19: a population‐based retrospective cohort study
Abstract Sodium‐glucose co‐transporter‐2 (SGLT2) inhibitors are widely prescribed in
people with type 2 diabetes. We aimed to investigate whether SGLT2 inhibitor prescription is …
people with type 2 diabetes. We aimed to investigate whether SGLT2 inhibitor prescription is …