Paternal impact on the life course development of obesity and type 2 diabetes in the offspring

GC Sharp, DA Lawlor - Diabetologia, 2019 - Springer
The aetiologies of obesity and type 2 diabetes are incredibly complex, but the potential role
of paternal influences remains relatively understudied. A better understanding of paternal …

Non-linear mendelian randomization: detection of biases using negative controls with a focus on BMI, vitamin D and ldl cholesterol

FW Hamilton, DA Hughes, W Spiller, K Tilling… - European Journal of …, 2024 - Springer
Mendelian randomisation (MR) is an established technique in epidemiological investigation,
using the principle of random allocation of genetic variants at conception to estimate the …

Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income

WD Hill, NM Davies, SJ Ritchie, NG Skene… - Nature …, 2019 - nature.com
Socioeconomic position (SEP) is a multi-dimensional construct reflecting (and influencing)
multiple socio-cultural, physical, and environmental factors. In a sample of 286,301 …

Reflection on modern methods: five myths about measurement error in epidemiological research

M Van Smeden, TL Lash… - International journal of …, 2020 - academic.oup.com
Epidemiologists are often confronted with datasets to analyse which contain measurement
error due to, for instance, mistaken data entries, inaccurate recordings and measurement …

[책][B] A first course in causal inference

P Ding - 2024 - books.google.com
The past decade has witnessed an explosion of interest in research and education in causal
inference, due to its wide applications in biomedical research, social sciences, artificial …

[HTML][HTML] Advances in methodologies of negative controls: a sco** review

Q Yang, Z Yang, X Cai, H Zhao, J Jia, F Sun - Journal of Clinical …, 2024 - Elsevier
Objective Negative control is considered an important tool to mitigate biases in
observational studies. The aim of this sco** review was to summarize current …

Prevention of coronavirus disease 2019 among older adults receiving pneumococcal conjugate vaccine suggests interactions between Streptococcus pneumoniae …

JA Lewnard, KJ Bruxvoort, H Fischer… - The Journal of …, 2022 - academic.oup.com
Background While secondary pneumococcal pneumonia occurs less commonly after
coronavirus disease 2019 (COVID-19) than after other viral infections, it remains unclear …

Associations of maternal quitting, reducing, and continuing smoking during pregnancy with longitudinal fetal growth: Findings from Mendelian randomization and …

JS Brand, R Gaillard, J West, RRC McEachan… - PLoS …, 2019 - journals.plos.org
Background Maternal smoking during pregnancy is an established risk factor for low infant
birth weight, but evidence on critical exposure windows and timing of fetal growth restriction …

The use of negative control outcomes in Mendelian randomization to detect potential population stratification

E Sanderson, TG Richardson, G Hemani… - International journal …, 2021 - academic.oup.com
A key assumption of Mendelian randomization (MR) analysis is that there is no association
between the genetic variants used as instruments and the outcome other than through the …

Sodium‐glucose co‐transporter‐2 inhibitors and susceptibility to COVID‐19: a population‐based retrospective cohort study

C Sainsbury, J Wang, K Gokhale… - Diabetes, Obesity …, 2021 - Wiley Online Library
Abstract Sodium‐glucose co‐transporter‐2 (SGLT2) inhibitors are widely prescribed in
people with type 2 diabetes. We aimed to investigate whether SGLT2 inhibitor prescription is …