Ruminococcus gnavus: friend or foe for human health

EH Crost, E Coletto, A Bell… - FEMS Microbiology …, 2023 - academic.oup.com
Ruminococcus gnavus was first identified in 1974 as a strict anaerobe in the gut of healthy
individuals, and for several decades, its study has been limited to specific enzymes or …

Biochemical and structural basis of sialic acid utilization by gut microbes

A Bell, E Severi, CD Owen, D Latousakis… - Journal of Biological …, 2023 - ASBMB
The human gastrointestinal (GI) tract harbors diverse microbial communities collectively
known as the gut microbiota that exert a profound impact on human health and disease. The …

The impact of gut microbiome enterotypes on ulcerative colitis: identifying key bacterial species and revealing species co-occurrence networks using machine learning

X Wu, T Zhang, TS Zhang, S Park - Gut Microbes, 2024 - Taylor & Francis
Ulcerative colitis (UC) is a chronic inflammatory intestinal disease affecting the colon and
rectum, with its pathogenesis attributed to genetic background, environmental factors, and …

[HTML][HTML] The human gut symbiont Ruminococcus gnavus displays strain-specific exopolysaccharides modulating the host immune response

V Laplanche, S Armiento, I Speciale, T Šuligoj… - Carbohydrate …, 2025 - Elsevier
Ruminococcus gnavus is a prevalent member of the human gut microbiota and over-
represented in inflammatory bowel diseases. R. gnavus ATCC 29149 was previously shown …

Sialic acid diversity in the human gut: molecular impacts and tools for future discovery

OM Sokolovskaya, MW Tan, DW Wolan - Current Opinion in Structural …, 2022 - Elsevier
Sialic acids are a family of structurally related sugars that are prevalent in mucosal surfaces,
including the human intestine. In the gut, sialic acids have diverse biological roles at the …

Degradation of gene silencer is essential for expression of foreign genes and bacterial colonization of the mammalian gut

J Choi, M Schmukler… - Proceedings of the …, 2022 - National Acad Sciences
Horizontal gene transfer drives bacterial evolution. To confer new properties, horizontally
acquired genes must overcome gene silencing by nucleoid-associated proteins, such as the …

Molecular recognition insights of sialic acid glycans by distinct receptors unveiled by NMR and molecular modeling

CO Soares, AS Grosso, J Ereño-Orbea… - Frontiers in Molecular …, 2021 - frontiersin.org
All cells are decorated with a highly dense and complex structure of glycan chains, which
are mostly attached to proteins and lipids. In this context, sialic acids are a family of nine …

Genome-wide association reveals host-specific genomic traits in Escherichia coli

SK Tiwari, BCL van der Putten, TM Fuchs, TN Vinh… - BMC biology, 2023 - Springer
Background Escherichia coli is an opportunistic pathogen which colonizes various host
species. However, to what extent genetic lineages of E. coli are adapted or restricted to …

Nutrient acquisition strategies by gut microbes

MK Muramatsu, SE Winter - Cell Host & Microbe, 2024 - cell.com
The composition and function of the gut microbiota are intimately tied to nutrient acquisition
strategies and metabolism, with significant implications for host health. Both dietary and host …

The role of the mucin-glycan foraging Ruminococcus gnavus in the communication between the gut and the brain

E Coletto, D Latousakis, MG Pontifex, EH Crost… - Gut …, 2022 - Taylor & Francis
Ruminococcus gnavus is a prevalent member of the human gut microbiota, which is over-
represented in inflammatory bowel disease and neurological disorders. We previously …