Body weight is determined by a balance between food intake and energy expenditure.
Multiple neural circuits in the brain have evolved to process information about food, food …

Aberrant regulation of oxytocin signaling is associated with the etiology of
neurodevelopmental disorders. Synaptic dysfunctions in neurodevelopmental disorders are …

The neuropeptide kisspeptin is necessary for reproduction, fertility, and puberty. Here, we
show strong kisspeptin innervation of hypothalamic anorexigenic proopiomelanocortin …

Histaminergic neurons in the tuberomammilary nucleus (TMN) of the hypothalamus form a
widely projecting, wake-active network that sustains arousal. Yet most histaminergic …

Key factors driving eating behavior are hunger and satiety, which are controlled by a
complex interplay of central neurotransmitter systems and peripheral stimuli. The lipid …

Wakefulness and consciousness depend on perturbation of the cortical soliloquy. Ascending
activation of the cerebral cortex is characteristic for both waking and paradoxical (REM) …

Narcolepsy is a chronic, long-term neurological disorder characterized by a decreased
ability to regulate sleep–wake cycles. Some clinical symptoms enter into differential …

The neurosurgical endeavor to treat psychiatric patients may have been part of human
history since its beginning. The modern era of psychosurgery can be traced to the heroic …

Thyrotropin-releasing hormone (TRH) is an important endocrine agent that regulates the
function of cells in the anterior pituitary and the central and peripheral nervous systems. By …

The treatment options currently available for narcolepsy are often unsatisfactory due to
suboptimal efficacy, troublesome side effects, development of drug tolerance, and …