In primary Sjögren syndrome (pSS), the function of the salivary glands is often considerably
reduced. Multiple innate immune pathways are likely dysregulated in the salivary gland …

Relevant reviews highlight the association between dysfunctional mitochondria and
inflammation, but few studies address the contribution of mitochondria and mitochondria …

Mucins (MUC) protect epithelial barriers from environmental insult to maintain homeostasis.
However, their aberrant overexpression and glycosylation in various malignancies facilitate …

Sjögren's syndrome is a chronic autoimmune disorder characterized by lymphocytic
infiltration and hypofunction of salivary and lacrimal glands. This loss of salivary function …

Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by chronic
inflammation of the salivary and lacrimal glands and extra-glandular lesions. Adaptive …

Mucins are highly O-glycosylated glycoproteins that carry a heterogenous variety of O-
glycan structures. Tumor cells tend to overexpress specific mucins, such as the cell surface …

While the importance of Toll‐like receptor (TLR) signaling is well established in many
autoimmune diseases, the role of TLR activation in Sjögren's syndrome (SS) is poorly …

Sjögren's syndrome is a systemic autoimmune disease characterized by dysfunction of the
affected exocrine glands. Lymphocytic infiltration within the inflamed glands and aberrant B …

Sjögren's syndrome (SS) is an autoimmune disease that mainly affects salivary glands (SG)
and is characterized by overactivation of the type I interferon (IFN) pathway. Type I IFNs can …

Salivary gland (SG) acinar-cells are susceptible to endoplasmic reticulum (ER) stress
related to their secretory activity and the complexity of synthesized secretory products. SGs …