Positron emission tomography (PET) constitutes a functional imaging technique that is
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …

The role of fluorine in drug design and development is expanding rapidly as we learn more
about the unique properties associated with this unusual element and how to deploy it with …

Diverse radiochemistry is an essential component of nuclear medicine; this includes
imaging techniques such as positron emission tomography (PET). As such, PET can track …

Taking into account the vast arrays of fluorinated motifs known, 11 this review will be limited
to the monofluorination of organic compounds, ie, synthetic methods allowing the …

Over the past decade, the most significant, conceptual advances in the field of fluorination
were enabled most prominently by organo‐and transition‐metal catalysis. The most …

Positron emission tomography (PET) is a molecular imaging technology that provides
quantitative information about function and metabolism in biological processes in vivo for …

Fluorinated organic compounds increasingly gain importance in numerous areas of
chemistry and everyday life. Building blocks which contain fluorinated entities are of high …

In recent years, there has been a dramatic increase in available methods for the installation
of fluorine and fluorine-containing functional groups in organic molecules, 1− 4 and the …

Fluorine-18 is the most frequently used radioisotope in positron emission tomography (PET)
radiopharmaceuticals in both clinical and preclinical research. Its physical and nuclear …

Fluorination reactions of medicinal and biologically-active compounds will be discussed.
Late stage fluorination strategies of medicinal targets have recently attracted considerable …