[HTML][HTML] In vitro fluidic systems: Applying shear stress on endothelial cells
F Meng, H Cheng, J Qian, X Dai, Y Huang… - Medicine in Novel …, 2022 - Elsevier
Endothelial cells (ECs) that reside on the surface of blood vessels are constantly exposed to
mechanical stimulation, including shear stress. Fluid shear stress (FSS) controls multiple …
mechanical stimulation, including shear stress. Fluid shear stress (FSS) controls multiple …
Mechanical regulation of the early stages of angiogenesis
S Barrasa-Ramos, CA Dessalles… - Journal of the …, 2022 - royalsocietypublishing.org
Favouring or thwarting the development of a vascular network is essential in fields as
diverse as oncology, cardiovascular disease or tissue engineering. As a result …
diverse as oncology, cardiovascular disease or tissue engineering. As a result …
Extracellular matrix stiffness regulates microvascular stability by controlling endothelial paracrine signaling to determine pericyte fate
Y Yu, Y Leng, X Song, J Mu, L Ma, L Yin… - … and Vascular Biology, 2023 - Am Heart Assoc
BACKGROUND: The differentiation of pericytes into myofibroblasts causes microvascular
degeneration, ECM (extracellular matrix) accumulation, and tissue stiffening, characteristics …
degeneration, ECM (extracellular matrix) accumulation, and tissue stiffening, characteristics …
[HTML][HTML] A micro-channel array in a tissue engineered vessel graft guides vascular morphogenesis for anastomosis with self-assembled vascular networks
Vascularization of 3D engineered tissues poses a great challenge in the field of tissue
engineering. One promising approach for vascularizing engineered tissue is cocultivation …
engineering. One promising approach for vascularizing engineered tissue is cocultivation …
Exploring endothelial expansion on a chip
Angiogenesis is the development of new blood vessels from the existing vasculature. Its
malfunction leads to the development of cancers and cardiovascular diseases qualified by …
malfunction leads to the development of cancers and cardiovascular diseases qualified by …
Microfluidic organ chip of fluid–solid dynamic curved interface
Dynamic curved interfaces are fundamental and ubiquitous structures in biological systems.
However, replicating the structure and function associated with these interfaces for …
However, replicating the structure and function associated with these interfaces for …
A review of functional analysis of endothelial cells in flow chambers
The vascular endothelial cells constitute the innermost layer. The cells are exposed to
mechanical stress by the flow, causing them to express their functions. To elucidate the …
mechanical stress by the flow, causing them to express their functions. To elucidate the …
Replacement in angiogenesis research: Studying mechanisms of blood vessel development by animal-free in vitro, in vivo and in silico approaches
MW Laschke, Y Gu, MD Menger - Frontiers in physiology, 2022 - frontiersin.org
Angiogenesis, the development of new blood vessels from pre-existing ones, is an essential
process determining numerous physiological and pathological conditions. Accordingly …
process determining numerous physiological and pathological conditions. Accordingly …
Soluble vascular endothelial glycocalyx proteoglycans as potential therapeutic targets in inflammatory diseases
Reducing the activity of cytokines and leukocyte extravasation is an emerging therapeutic
strategy to limit tissue‐damaging inflammatory responses and restore immune homeostasis …
strategy to limit tissue‐damaging inflammatory responses and restore immune homeostasis …
A nanoporous hydrogel-based model to study chemokine gradient-driven angiogenesis under luminal flow
The growth of new blood vessels through angiogenesis is a highly coordinated process,
which is initiated by chemokine gradients that activate endothelial cells within a perfused …
which is initiated by chemokine gradients that activate endothelial cells within a perfused …