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The role of M1/M2 macrophage polarization in rheumatoid arthritis synovitis
Innate and adaptive immunity represent a harmonic counterbalanced system involved in the
induction, progression, and possibly resolution of the inflammatory reaction that characterize …
induction, progression, and possibly resolution of the inflammatory reaction that characterize …
Estrogen receptor signaling in the immune system
The immune system functions in a sexually dimorphic manner, with females exhibiting more
robust immune responses than males. However, how female sex hormones affect immune …
robust immune responses than males. However, how female sex hormones affect immune …
Macrophage M1/M2 polarization and rheumatoid arthritis: a systematic review
Background and aim Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory
disease; the clinical manifestations are correlated with continuum multiarticular synovitis …
disease; the clinical manifestations are correlated with continuum multiarticular synovitis …
The interplay between immunosenescence and age-related diseases
The aging immune system (immunosenescence) has been implicated with increased
morbidity and mortality in the elderly. Of note, T cell aging and low-grade inflammation …
morbidity and mortality in the elderly. Of note, T cell aging and low-grade inflammation …
Macrophage heterogeneity in the context of rheumatoid arthritis
Macrophages are very important in the pathogenesis of rheumatoid arthritis (RA). The
increase in the number of sublining macrophages in the synovium is an early hallmark of …
increase in the number of sublining macrophages in the synovium is an early hallmark of …
Pattern of human monocyte subpopulations in health and disease
A Ożańska, D Szymczak, J Rybka - Scandinavian journal of …, 2020 - Wiley Online Library
Monocytes are important cells of the innate system. They are a heterogeneous type of cells
consisting of phenotypically and functionally distinct subpopulations, which play a specific …
consisting of phenotypically and functionally distinct subpopulations, which play a specific …
Monocyte conversion during inflammation and injury
Monocytes are circulating leukocytes important in both innate and adaptive immunity,
primarily functioning in immune defense, inflammation, and tissue remodeling. There are 2 …
primarily functioning in immune defense, inflammation, and tissue remodeling. There are 2 …
Monocytes in rheumatoid arthritis: Circulating precursors of macrophages and osteoclasts and, their heterogeneity and plasticity role in RA pathogenesis
Rheumatoid arthritis (RA) is a chronic systemic, autoimmune and inflammatory disease
represented as synovitis, pannus formation, adjacent bone erosions, and joint destruction …
represented as synovitis, pannus formation, adjacent bone erosions, and joint destruction …
The many facets of macrophages in rheumatoid arthritis
Macrophages are central to the pathophysiology of rheumatoid arthritis (RA). They constitute
the main source of pro-inflammatory cytokines and chemokines such as TNF and IL-1β, they …
the main source of pro-inflammatory cytokines and chemokines such as TNF and IL-1β, they …
Autoimmune diseases and atherosclerotic cardiovascular disease
Autoimmune diseases are associated with a dramatically increased risk of atherosclerotic
cardiovascular disease and its clinical manifestations. The increased risk is consistent with …
cardiovascular disease and its clinical manifestations. The increased risk is consistent with …