Asymmetric catalysis mediated by synthetic peptides, version 2.0: expansion of scope and mechanisms

AJ Metrano, AJ Chinn, CR Shugrue, EA Stone… - Chemical …, 2020 - ACS Publications
Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

DCEO biotechnology: tools to design, construct, evaluate, and optimize the metabolic pathway for biosynthesis of chemicals

X Chen, C Gao, L Guo, G Hu, Q Luo, J Liu… - Chemical …, 2018 - ACS Publications
Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates …

Model organisms for genetics in the domain Archaea: methanogens, halophiles, Thermococcales and Sulfolobales

JA Leigh, SV Albers, H Atomi… - FEMS microbiology …, 2011 - academic.oup.com
The tree of life is split into three main branches: eukaryotes, bacteria, and archaea. Our
knowledge of eukaryotic and bacteria cell biology has been built on a foundation of studies …

[PDF][PDF] Osmoadaptation mechanisms in prokaryotes: distribution of compatible solutes

N Empadinhas, MS da Costa - Int Microbiol, 2008 - Citeseer
Microorganisms respond to osmotic stress mostly by accumulating compatible solutes, either
by uptake from the medium or by de novo synthesis. These osmotically active molecules …

Harnessing 13 C-labeled myo-inositol to interrogate inositol phosphate messengers by NMR

RK Harmel, R Puschmann, MN Trung, A Saiardi… - Chemical …, 2019 - pubs.rsc.org
Inositol poly-and pyrophosphates (InsPs and PP-InsPs) are an important group of
metabolites and mediate a wide range of processes in eukaryotic cells. To elucidate the …

Genomes of Thaumarchaeota from deep sea sediments reveal specific adaptations of three independently evolved lineages

M Kerou, RI Ponce-Toledo, R Zhao, SS Abby… - The ISME …, 2021 - academic.oup.com
Marine sediments represent a vast habitat for complex microbiomes. Among these,
ammonia oxidizing archaea (AOA) of the phylum Thaumarchaeota are one of the most …

Inositol polyphosphates, diphosphoinositol polyphosphates and phosphatidylinositol polyphosphate lipids: structure, synthesis, and development of probes for …

MD Best, H Zhang, GD Prestwich - Natural Product Reports, 2010 - pubs.rsc.org
Covering: 2006 up to June 2010, but also including representative examples of prior work
Polyphosphorylated myo-inositol compounds, including the inositol polyphosphates (InsPs) …

Structural basis for phosphatidylinositol-phosphate biosynthesis

OB Clarke, D Tomasek, CD Jorge, MB Dufrisne… - Nature …, 2015 - nature.com
Phosphatidylinositol is critical for intracellular signalling and anchoring of carbohydrates and
proteins to outer cellular membranes. The defining step in phosphatidylinositol biosynthesis …

Structural basis for catalysis in a CDP-alcohol phosphotransferase

G Sciara, OB Clarke, D Tomasek, B Kloss… - Nature …, 2014 - nature.com
The CDP-alcohol phosphotransferase (CDP-AP) family of integral membrane enzymes
catalyses the transfer of a substituted phosphate group from a CDP-linked donor to an …

X-ray structure of a CDP-alcohol phosphatidyltransferase membrane enzyme and insights into its catalytic mechanism

P Nogly, I Gushchin, A Remeeva, AM Esteves… - Nature …, 2014 - nature.com
Phospholipids have major roles in the structure and function of all cell membranes. Most
integral membrane proteins from the large CDP-alcohol phosphatidyltransferase family are …