Tissue engineering uses a combination of cell biology, chemistry, and biomaterials to
fabricate three dimensional (3D) tissues that mimic the architecture of extracellular matrix …

This review focuses on a somewhat unexplored strand of regenerative medicine, that is in
situ tissue engineering. In this approach manufactured scaffolds are implanted in the injured …

Background The regeneration of periodontal bone defect remains a vital clinical challenge.
To date, numerous biomaterials have been applied in this field. However, the immune …

This review explores state-of-the-art and new perspectives description of scaffold-based
strategies utilized in in-suit bone tissue engineering. The bone defects caused by severe …

Bone tissue engineering is becoming an ideal strategy to replace autologous bone grafts for
surgical bone repair, but the multihierarchical complexity of natural bone is still difficult to …

Over the past two decades in situ tissue engineering has emerged as a new approach
where biomaterials are used to harness the body's own stem/progenitor cells to regenerate …

The heterogeneity of native tissues requires complex materials to provide suitable
substitutes for model systems and replacement tissues. Functionally graded materials have …

In the field of tissue engineering, there are several issues to consider when designing
biomaterials for implants, including cellular interaction, good biocompatibility, and …

In situ tissue engineering is a powerful strategy for the treatment of bone defects. It could
overcome the limitations of traditional bone tissue engineering, which typically involves …

Stem-cell based therapy strategies are promising approaches for the treatment of bone
defects. However, extensive cell expansion steps, the low rate of cell survival and …