[HTML][HTML] Targeting the Warburg effect: A revisited perspective from molecular mechanisms to traditional and innovative therapeutic strategies in cancer
M Liao, D Yao, L Wu, C Luo, Z Wang, J Zhang… - … Pharmaceutica Sinica B, 2024 - Elsevier
Cancer reprogramming is an important facilitator of cancer development and survival, with
tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation …
tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation …
Advancing cell surface modification in mammalian cells with synthetic molecules
Biological cells, being the fundamental entities of life, are widely acknowledged as intricate
living machines. The manipulation of cell surfaces has emerged as a progressively …
living machines. The manipulation of cell surfaces has emerged as a progressively …
Site-selected in situ polymerization for living cell surface engineering
Y Zhong, L Xu, C Yang, L Xu, G Wang, Y Guo… - Nature …, 2023 - nature.com
The construction of polymer-based mimicry on cell surface to manipulate cell behaviors and
functions offers promising prospects in the field of biotechnology and cell therapy. However …
functions offers promising prospects in the field of biotechnology and cell therapy. However …
Bioinspired peptide adhesion on Ti implants alleviates wear particle-induced inflammation and improves interfacial osteogenesis
In the inflammatory peri-implant microenvironment, excessive polarization of macrophages
to the proinflammatory M1 phenotype can trigger the secretion of inflammatory cytokines …
to the proinflammatory M1 phenotype can trigger the secretion of inflammatory cytokines …
Specific recognition to create nanofunctionalized cells for precise functions
TK Zhang, W Geng, YQ Huang, FZ Wang, G Tian… - Coordination Chemistry …, 2024 - Elsevier
Specific recognition sites exist in cells to bring about encapsulation and consequent
enhancements in stability and selectivity. Methods to create nanofunctionalized cells have …
enhancements in stability and selectivity. Methods to create nanofunctionalized cells have …
Local detection of pH-induced disaggregation of biocompatible micelles by fluorescence switch ON
G Battistelli, M Proetto, A Mavridi-Printezi… - Chemical …, 2022 - pubs.rsc.org
Fluorogenic nanoparticles (NPs) able to sense different physiological environments and
respond with disaggregation and fluorescence switching OFF/ON are powerful tools in …
respond with disaggregation and fluorescence switching OFF/ON are powerful tools in …
Integrating Metabolic Oligosaccharide Engineering and SPAAC Click Chemistry for Constructing Fibrinolytic Cell Surfaces
To effectively solve the problem of significant loss of transplanted cells caused by
thrombosis during cell transplantation, this study simulates the human fibrinolytic system and …
thrombosis during cell transplantation, this study simulates the human fibrinolytic system and …
Covalent recruitment of polymers and nanoparticles onto glycan-engineered cells enhances gene delivery during short exposure
Non-viral gene delivery with cationic polymers/nanoparticles relies on iterative optimization
of the carrier to achieve delivery. Here we demonstrate, instead, that precision engineering …
of the carrier to achieve delivery. Here we demonstrate, instead, that precision engineering …
生体直交型反応による細胞とハイドロゲルの融合, 医療応用を目指して
長濱宏治 - ファルマシア, 2021 - jstage.jst.go.jp
抄録 細胞が本来もたない反応性官能基を細胞に導入することは, 生体直交型反応を介した機能性
分子による細胞エンジニアリングを可能とし, 細胞の機能制御や新規機能を付与した細胞の創出に …
分子による細胞エンジニアリングを可能とし, 細胞の機能制御や新規機能を付与した細胞の創出に …