Diamond quantum thermometry: From foundations to applications
Diamond quantum thermometry exploits the optical and electrical spin properties of colour
defect centres in diamonds and, acts as a quantum sensing method exhibiting ultrahigh …
defect centres in diamonds and, acts as a quantum sensing method exhibiting ultrahigh …
Pluripotent-stem-cell-derived hepatic cells: hepatocytes and organoids for liver therapy and regeneration
A Messina, E Luce, M Hussein… - Cells, 2020 - mdpi.com
The liver is a very complex organ that ensures numerous functions; it is thus susceptible to
multiple types of damage and dysfunction. Since 1983, orthotopic liver transplantation (OLT) …
multiple types of damage and dysfunction. Since 1983, orthotopic liver transplantation (OLT) …
[HTML][HTML] Characterization of human colon organoids from inflammatory bowel disease patients
E d'Aldebert, M Quaranta, M Sébert… - Frontiers in cell and …, 2020 - frontiersin.org
Inflammatory Bowel Diseases (IBD) are chronic inflammatory disorders, where epithelial
defects drive, at least in part, some of the pathology. We reconstituted human intestinal …
defects drive, at least in part, some of the pathology. We reconstituted human intestinal …
D-CryptO: deep learning-based analysis of colon organoid morphology from brightfield images
L Abdul, J Xu, A Sotra, A Chaudary, J Gao… - Lab on a Chip, 2022 - pubs.rsc.org
Stem cell-derived organoids are a promising tool to model native human tissues as they
resemble human organs functionally and structurally compared to traditional monolayer cell …
resemble human organs functionally and structurally compared to traditional monolayer cell …
[HTML][HTML] Lung cancer organoids, a promising model still with long way to go
H Ma, Y Zhu, R Zhou, Y Yu, Z **ao, H Zhang - Critical Reviews in Oncology …, 2022 - Elsevier
Lung cancer organoids (LCOs) have sprung up in more and more researching fields,
because of their ability to recapitulate the three-dimensional structure and functions of the in …
because of their ability to recapitulate the three-dimensional structure and functions of the in …
KIT promotes tumor stroma formation and counteracts tumor-suppressive TGFβ signaling in colorectal cancer
E Küçükköse, NA Peters, I Ubink, VAM van Keulen… - Cell death & …, 2022 - nature.com
Expression profiling has identified four consensus molecular subtypes (CMS1-4) in
colorectal cancer (CRC). The receptor tyrosine kinase KIT has been associated with the …
colorectal cancer (CRC). The receptor tyrosine kinase KIT has been associated with the …
[HTML][HTML] Living biobank-based cancer organoids: prospects and challenges in cancer research
H Li, H Liu, K Chen - Cancer Biology & Medicine, 2022 - ncbi.nlm.nih.gov
Biobanks bridge the gap between basic and translational research. Traditional cancer
biobanks typically contain normal and tumor tissues, and matched blood. However …
biobanks typically contain normal and tumor tissues, and matched blood. However …
[HTML][HTML] Autophagy Contributes to Homeostasis in Esophageal Epithelium Where High Autophagic Vesicle Level Marks Basal Cells With Limited Proliferation and …
Background & Aims Autophagy plays roles in esophageal pathologies both benign and
malignant. Here, we aim to define the role of autophagy in esophageal epithelial …
malignant. Here, we aim to define the role of autophagy in esophageal epithelial …
Human Colonoid–Myofibroblast Coculture for Study of Apical Na+/H+ Exchangers of the Lower Cryptal Neck Region
A Salari, K Zhou, K Nikolovska, U Seidler… - International Journal of …, 2023 - mdpi.com
Cation and anion transport in the colonocyte apical membrane is highly spatially organized
along the cryptal axis. Because of lack of experimental accessibility, information about the …
along the cryptal axis. Because of lack of experimental accessibility, information about the …
Loss of mismatch repair promotes a direct selective advantage in human stem cells
K Madden-Hennessey, D Gupta, AA Radecki, C Guild… - Stem cell reports, 2022 - cell.com
Lynch syndrome (LS) is the most common hereditary form of colon cancer, resulting from a
germline mutation in a DNA mismatch repair (MMR) gene. Loss of MMR in cells establishes …
germline mutation in a DNA mismatch repair (MMR) gene. Loss of MMR in cells establishes …