Little fish, big data: zebrafish as a model for cardiovascular and metabolic disease

P Gut, S Reischauer, DYR Stainier… - Physiological …, 2017‏ - journals.physiology.org
The burden of cardiovascular and metabolic diseases worldwide is staggering. The
emergence of systems approaches in biology promises new therapies, faster and cheaper …

[HTML][HTML] Reimagining safe lithium applications in the living environment and its impacts on human, animal, and plant system

N Shakoor, M Adeel, MA Ahmad, M Zain… - Environmental Science …, 2023‏ - Elsevier
Lithium's (Li) ubiquitous distribution in the environment is a rising concern due to its rapid
proliferation in the modern electronic industry. Li enigmatic entry into the terrestrial food …

RNA‐seq of the aging brain in the short‐lived fish N. furzeri – conserved pathways and novel genes associated with neurogenesis

M Baumgart, M Groth, S Priebe, A Savino, G Testa… - Aging cell, 2014‏ - Wiley Online Library
The brains of teleost fish show extensive adult neurogenesis and neuronal regeneration.
The patterns of gene regulation during fish brain aging are unknown. The short‐lived teleost …

[HTML][HTML] Environmental chemicals affect circadian rhythms: An underexplored effect influencing health and fitness in animals and humans

X Zheng, K Zhang, Y Zhao, K Fent - Environment international, 2021‏ - Elsevier
Circadian rhythms control the life of virtually all organisms. They regulate numerous aspects
ranging from cellular processes to reproduction and behavior. Besides the light-dark cycle …

The circadian clock and glucocorticoids–interactions across many time scales

T Dickmeis, BD Weger, M Weger - Molecular and cellular endocrinology, 2013‏ - Elsevier
Glucocorticoids are steroid hormones of the adrenal gland that are an integral component of
the stress response and regulate many physiological processes, including metabolism and …

[HTML][HTML] Stem cells and the circadian clock

M Weger, N Diotel, AC Dorsemans, T Dickmeis… - Developmental …, 2017‏ - Elsevier
The circadian timing system is a complex biological network of interacting circadian clocks
that regulates 24 h rhythms of behavioral and physiological processes. One intriguing …

Lipid metabolism alteration by endocrine disruptors in animal models: an overview

F Maradonna, O Carnevali - Frontiers in endocrinology, 2018‏ - frontiersin.org
Exposure to potential Endocrine Disrupting Chemicals (EDCs) pose a documented risk to
both wildlife and human health. Many studies so far described declining sperm counts …

Lithium and bipolar disorder: impacts from molecular to behavioural circadian rhythms

J Moreira, PA Geoffroy - Chronobiology international, 2016‏ - Taylor & Francis
Bipolar disorder (BD) is a severe and common psychiatric disorder. BD pathogenesis,
clinical manifestations and relapses are associated with numerous circadian rhythm …

Circadian rhythmicity and light sensitivity of the zebrafish brain

HA Moore, D Whitmore - PloS one, 2014‏ - journals.plos.org
Traditionally, circadian clocks have been thought of as a neurobiological phenomenon. This
view changed somewhat over recent years with the discovery of peripheral tissue circadian …

Zebrafish: A marvel of high-throughput biology for 21st century toxicology

SM Bugel, RL Tanguay, A Planchart - Current environmental health reports, 2014‏ - Springer
The evolutionary conservation of genomic, biochemical, and developmental features
between zebrafish and humans is gradually coming into focus, with the end result that the …