The prevalence and incidence of dementia due to Alzheimer's disease: a systematic review and meta-analysis

KM Fiest, JI Roberts, CJ Maxwell, DB Hogan… - Canadian Journal of …, 2016‏ - cambridge.org
BackgroundUpdated information on the epidemiology of dementia due to Alzheimer's
disease (AD) is needed to ensure that adequate resources are available to meet current and …

A systematic review of prevalence studies of dementia in Parkinson's disease

D Aarsland, J Zaccai, C Brayne - Movement disorders: official …, 2005‏ - Wiley Online Library
Substantial variation in the prevalence of dementia in Parkinson's disease (PDD) has been
reported. The aim of this study was to review systematically and critically previous studies of …

New insights into the genetic etiology of Alzheimer's disease and related dementias

C Bellenguez, F Küçükali, IE Jansen, L Kleineidam… - Nature …, 2022‏ - nature.com
Abstract Characterization of the genetic landscape of Alzheimer's disease (AD) and related
dementias (ADD) provides a unique opportunity for a better understanding of the associated …

Prevalence of dementia in India: National and state estimates from a nationwide study

J Lee, E Meijer, KM Langa, M Ganguli… - Alzheimer's & …, 2023‏ - Wiley Online Library
Introduction Prior estimates of dementia prevalence in India were based on samples from
selected communities, inadequately representing the national and state populations …

Sleep architecture, obstructive sleep apnea, and cognitive function in adults

MP Pase, S Harrison, JR Misialek, CE Kline… - JAMA network …, 2023‏ - jamanetwork.com
Importance Good sleep is essential for health, yet associations between sleep and dementia
risk remain incompletely understood. The Sleep and Dementia Consortium was established …

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

G Davies, M Lam, SE Harris, JW Trampush… - Nature …, 2018‏ - nature.com
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

R Sims, SJ Van Der Lee, AC Naj, C Bellenguez… - Nature …, 2017‏ - nature.com
We identified rare coding variants associated with Alzheimer's disease in a three-stage case–
control study of 85,133 subjects. In stage 1, we genotyped 34,174 samples using a whole …

A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease

K Huang, E Marcora, AA Pimenova, AF Di Narzo… - Nature …, 2017‏ - nature.com
A genome-wide survival analysis of 14,406 Alzheimer's disease (AD) cases and 25,849
controls identified eight previously reported AD risk loci and 14 novel loci associated with …

Clonal hematopoiesis is associated with protection from Alzheimer's disease

H Bouzid, JA Belk, M Jan, Y Qi, C Sarnowski, S Wirth… - Nature Medicine, 2023‏ - nature.com
Clonal hematopoiesis of indeterminate potential (CHIP) is a premalignant expansion of
mutated hematopoietic stem cells. As CHIP-associated mutations are known to alter the …

Vitamin D and the risk of dementia and Alzheimer disease

TJ Littlejohns, WE Henley, IA Lang, C Annweiler… - Neurology, 2014‏ - neurology.org
Objective: To determine whether low vitamin D concentrations are associated with an
increased risk of incident all-cause dementia and Alzheimer disease. Methods: One …