[HTML][HTML] Ultrasound-responsive cavitation nuclei for therapy and drug delivery
K Kooiman, S Roovers, SAG Langeveld… - Ultrasound in medicine …, 2020 - Elsevier
Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …
Ultrasound technologies for imaging and modulating neural activity
Visualizing and perturbing neural activity on a brain-wide scale in model animals and
humans is a major goal of neuroscience technology development. Established electrical and …
humans is a major goal of neuroscience technology development. Established electrical and …
Safety and feasibility of repeated and transient blood–brain barrier disruption by pulsed ultrasound in patients with recurrent glioblastoma
A Idbaih, M Canney, L Belin, C Desseaux, A Vignot… - Clinical Cancer …, 2019 - AACR
Purpose: The blood–brain barrier (BBB) limits the efficacy of drug therapies for glioblastoma
(GBM). Preclinical data indicate that low-intensity pulsed ultrasound (LIPU) can transiently …
(GBM). Preclinical data indicate that low-intensity pulsed ultrasound (LIPU) can transiently …
Drug delivery system based on nanobubbles
J **, L Yang, F Chen, N Gu - Interdisciplinary Materials, 2022 - Wiley Online Library
Ultrasound (US) medical technology is widely used due to its advantages of safety, speed,
and low cost. With the rapid development of biomedical nanotechnology …
and low cost. With the rapid development of biomedical nanotechnology …
Characterization of the responses of brain macrophages to focused ultrasound-mediated blood–brain barrier opening
AR Kline-Schoder, S Chintamen, MJ Willner… - Nature Biomedical …, 2024 - nature.com
The opening of the blood–brain barrier (BBB) by focused ultrasound (FUS) coupled with
intravenously injected microbubbles can be leveraged as a form of immunotherapy for the …
intravenously injected microbubbles can be leveraged as a form of immunotherapy for the …
Evolving drug delivery strategies to overcome the blood brain barrier
The blood-brain barrier (BBB) poses a unique challenge for drug delivery to the central
nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial …
nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial …
Mechanical and biological effects of ultrasound: a review of present knowledge
Ultrasound is widely used for medical diagnosis and increasingly for therapeutic purposes.
An understanding of the bio-effects of sonography is important for clinicians and scientists …
An understanding of the bio-effects of sonography is important for clinicians and scientists …
The mediodorsal thalamus: an essential partner of the prefrontal cortex for cognition
Deficits in cognition are a core feature of many psychiatric conditions, including
schizophrenia, where the severity of such deficits is a strong predictor of long-term outcome …
schizophrenia, where the severity of such deficits is a strong predictor of long-term outcome …
Therapeutic oxygen delivery by perfluorocarbon-based colloids
MP Krafft, JG Riess - Advances in colloid and interface science, 2021 - Elsevier
After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …
Ultrasound treatment of neurological diseases—current and emerging applications
Like cardiovascular disease and cancer, neurological disorders present an increasing
challenge for an ageing population. Whereas nonpharmacological procedures are routine …
challenge for an ageing population. Whereas nonpharmacological procedures are routine …