There is considerable ambiguity in the use of terminology when referring to orofacial clefts
(OFCs). Many clinicians incorrectly refer to OFCs as deformities, which are said to be the …

Neural crest cells appear early during embryogenesis and give rise to many structures in the
mature adult. In particular, a specific population of neural crest cells migrates to and …

El trastorno del espectro autista (TEA) fue descrito por primera vez en 1943 por Leo Kanner,
y desde entonces se han publicado 18 490 artículos, los cuales han sido citados 48 416 …

Disruption of the Hedgehog signaling pathway has been implicated as an important
molecular mechanism in the pathogenesis of fetal alcohol syndrome. In severe cases, the …

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Aims Cardiac inflammation has been suggested to be regulated by the sympathetic nervous
system (SNS). However, due to the lack of methodology to surgically eliminate the …

Marked by incomplete division of the embryonic forebrain, holoprosencephaly is one of the
most common human developmental disorders. Despite decades of phenotype-driven …

Holoprosencephaly (HPE) is a complex genetic disorder of the develo** forebrain
characterized by high phenotypic and genetic heterogeneity. HPE was initially defined as an …

Holoprosencephaly (HPE) is the most common malformation of the prosencephalon in
humans. It is characterized by a continuum of structural brain anomalies resulting from the …

Developmental biologists rely on genetics-based approaches to understand the origins of
congenital abnormalities. Recent advancements in genomics have made it easier than ever …