Recent advances of Cp* Ir complexes for transfer hydrogenation: focus on formic acid/formate as hydrogen donors

YF Wei, Y Liang, R Luo, L Ouyang - Organic & Biomolecular Chemistry, 2023‏ - pubs.rsc.org
Transfer hydrogenation reactions offer synthetically powerful strategies to deliver various
hydrogenated compounds with the advantages of efficiency, atom economy, and …

[HTML][HTML] The acquisition of primary amines from alcohols through reductive amination over heterogeneous catalysts

H Huang, Y Wei, Y Cheng, S **ao, M Chen, Z Wei - Catalysts, 2023‏ - mdpi.com
The synthesis of primary amines via the reductive amination of alcohols involves a hydrogen-
borrowing or hydrogen-transfer mechanism, which consists of three main steps: alcohol …

Enantioselective total synthesis of (−)-himalensine a via a palladium and 4-hydroxyproline co-catalyzed desymmetrization of vinyl-bromide-tethered cyclohexanones

R Kučera, SR Ellis, K Yamazaki… - Journal of the …, 2023‏ - ACS Publications
Herein, we describe the convergent enantioselective total synthesis of himalensine A in 18
steps, enabled by a highly enantio-and diastereoselective construction of the morphan core …

Reductive aminomethylation using ammonium formate and methanol as N1 and C1 source: Direct synthesis of mono-and di-methylated amines

I Borthakur, S Nandi, Y Bilora, B Sadhu, S Kundu - ACS Catalysis, 2024‏ - ACS Publications
An Ir (III) complex catalyzed single and dual reductive amination followed by N-methylation
of aldehydes and ketones to synthesize N, N-dimethyl as well as N-methyl tertiary amines …

Mechanistic Investigations on Cp*CoIII-Catalyzed Quinoline Transfer Hydrogenation with Formic Acid

N Garg, P Dahiya, S Mallet-Ladeira, R Poli… - ACS …, 2024‏ - ACS Publications
The mechanism of the quinoline transfer hydrogenation (TH) by aqueous HCOOH under the
action of [Cp* Co (quinNH2) I]+(A*; quinNH2= 8-aminoquinoline) has been investigated by a …

Synthesis of Chiral Primary Amines via Enantioselective Reductive Amination: From Academia to Industry

Y Shi, N Rong, X Zhang, Q Yin - Synthesis, 2023‏ - thieme-connect.com
Chiral primary amines widely exist in drugs and are exceptionally important subunits or
synthons in the syntheses of chiral secondary and tertiary amines of medicinal interest …

A brief review: advancement in the synthesis of amine through the Leuckart reaction

Q Umar, M Luo - Reactions, 2023‏ - mdpi.com
This review presents a summary of reactions that take place during the “Leuckart-type
reaction”. The significance of, as well as recent advancements in, the synthesis of amines …

ZIF‐67 Derived Co/NC Nanoparticles Enable Catalytic Leuckart‐type Reductive Amination of Bio‐based Carbonyls to N‐Formyl Compounds

C Li, Y Meng, S Yang, H Li - ChemCatChem, 2021‏ - Wiley Online Library
It is of great significance to develop non‐precious metal catalysts with excellent catalytic
activity, stability, and acid resistance for biomass valorization. Herein, catalytic amination of …

Direct reductive amination of ketones with ammonium salt catalysed by Cp* Ir (iii) complexes bearing an amidato ligand

Z Dai, YM Pan, SG Wang, X Zhang… - Organic & Biomolecular …, 2021‏ - pubs.rsc.org
A series of half-sandwich Ir (III) complexes 1–6 bearing an amidato bidentate ligand were
conveniently synthesized and applied to the catalytic Leuckart–Wallach reaction to produce …

[HTML][HTML] Highly efficient synthesis of chiral β-amino phosphine derivatives via direct asymmetric reductive amination with ammonium salts and H2

Y Liu, L Wang, Y Li, B Ma, GQ Chen, X Zhang - Green Synthesis and …, 2022‏ - Elsevier
A highly efficient and enantioselective method for the asymmetric reductive amination of β-
keto phosphine derivatives was disclosed, and the corresponding β-amino phosphine …