Alcohol use disorder (AUD) is a highly prevalent but severely under-treated disorder, with
only three widely-approved pharmacotherapies. Given that AUD is a very heterogeneous …

Succinate is an important metabolite at the cross-road of several metabolic pathways, also
involved in the formation and elimination of reactive oxygen species. However, it is …

The alcohol withdrawal syndrome is a well‐known condition occurring after intentional or
unintentional abrupt cessation of heavy/constant drinking in patients suffering from alcohol …

Symptoms of alcohol withdrawal syndrome (AWS) may develop within 6–24 h after the
abrupt discontinuation or decrease of alcohol consumption. Symptoms can vary from …

Alcohol use disorders (AUDs) is one of the leading causes of disease and disability in
almost all European countries. Among the alcohol-related diseases, alcoholic liver disease …

Background Alcohol abuse and dependence represents a serious health problem
worldwide with social, interpersonal and legal interpolations. Benzodiazepines have been …

Drug use typically occurs within a social context, and social factors play an important role in
the initiation, maintenance and recovery from addictions. There is now accumulating …

The British Association for Psychopharmacology guidelines for the treatment of substance
abuse, harmful use, addiction and comorbidity with psychiatric disorders primarily focus on …

Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

Background Alcohol abuse and dependence represents a very serious health problem
worldwide with major social, interpersonal and legal interpolations. Pharmacological …