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Andrographolide, a natural anti-inflammatory agent: An Update
X Li, W Yuan, J Wu, J Zhen, Q Sun, M Yu - Frontiers in pharmacology, 2022 - frontiersin.org
Botanicals have attracted much attention in the field of anti-inflammatory due to their good
pharmacological activity and efficacy. Andrographis paniculata is a natural plant ingredient …
pharmacological activity and efficacy. Andrographis paniculata is a natural plant ingredient …
Role of Wnt signaling in adult hippocampal neurogenesis in health and disease
SB Arredondo, D Valenzuela-Bezanilla… - Frontiers in Cell and …, 2020 - frontiersin.org
Neurogenesis persists during adulthood in the dentate gyrus of the hippocampus. Signals
provided by the local hippocampal microenvironment support neural stem cell proliferation …
provided by the local hippocampal microenvironment support neural stem cell proliferation …
Is there a future for andrographolide to be an anti-inflammatory drug? Deciphering its major mechanisms of action
Andrographis paniculata has long been part of the traditional herbal medicine system in
Asia and in Scandinavia. Andrographolide was isolated as a major bioactive constituent of …
Asia and in Scandinavia. Andrographolide was isolated as a major bioactive constituent of …
Utilizing Andrographis paniculata leaves and roots by effective usage of the bioactive andrographolide and its nanodelivery: investigation of antikindling and …
To valorise the bioactive constituents abundant in leaves and other parts of medicinal plants
with the objective to minimize the plant-based wastes, this study was undertaken. The main …
with the objective to minimize the plant-based wastes, this study was undertaken. The main …
Loss of canonical Wnt signaling is involved in the pathogenesis of Alzheimer's disease
Alzheimer's disease (AD) is the most common form of dementia in the older population,
however, the precise cause of the disease is unknown. The neuropathology is characterized …
however, the precise cause of the disease is unknown. The neuropathology is characterized …
[HTML][HTML] Impact of micronutrients and nutraceuticals on cognitive function and performance in Alzheimer's disease
Alzheimer's disease (AD) is a major global health problem today and is the most common
form of dementia. AD is characterized by the formation of β-amyloid (Aβ) plaques and …
form of dementia. AD is characterized by the formation of β-amyloid (Aβ) plaques and …
Role of Wnt signaling in central nervous system injury
The central nervous system (CNS) is highly sensitive to external mechanical damage,
presenting a limited capacity for regeneration explained in part by its inability to restore …
presenting a limited capacity for regeneration explained in part by its inability to restore …
[HTML][HTML] Nature-derived compounds modulating Wnt/β-catenin pathway: a preventive and therapeutic opportunity in neoplastic diseases
The Wnt/β-catenin signaling is a conserved pathway that has a crucial role in embryonic and
adult life. Dysregulation of the Wnt/β-catenin pathway has been associated with diseases …
adult life. Dysregulation of the Wnt/β-catenin pathway has been associated with diseases …
Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20‐APP transgenic and wild‐type mice
Alzheimer's disease (AD) is a neurodegenerative pathology characterized by aggregates of
amyloid‐β (Aβ) and phosphorylated tau protein, synaptic dysfunction, and spatial memory …
amyloid‐β (Aβ) and phosphorylated tau protein, synaptic dysfunction, and spatial memory …
Targeting the Wnt/β-catenin pathway in neurodegenerative diseases: recent approaches and current challenges
Introduction Wnt/β-catenin signaling is an evolutionarily conserved pathway having a crucial
role in embryonic and adult life. Specifically, the Wnt/β-catenin axis is pivotal to the …
role in embryonic and adult life. Specifically, the Wnt/β-catenin axis is pivotal to the …