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[HTML][HTML] Systematic development of ionizable lipid nanoparticles for placental mRNA delivery using a design of experiments approach
Ionizable lipid nanoparticles (LNPs) have gained attention as mRNA delivery platforms for
vaccination against COVID-19 and for protein replacement therapies. LNPs enhance mRNA …
vaccination against COVID-19 and for protein replacement therapies. LNPs enhance mRNA …
Combining DoE and MASE: a winning strategy for the isolation of natural bioactive compounds from plant materials
The successes achieved in pursuing a nature-aided drug discovery (NADD) program are
many and well-known, but it is still considered a second-order approach. Biomass extraction …
many and well-known, but it is still considered a second-order approach. Biomass extraction …
Modeling, analysis, and optimization of dimensional accuracy of FDM-fabricated parts using definitive screening design and deep learning feedforward artificial neural …
Additive manufacturing (AM) technologies such as fused deposition modeling (FDM) rely on
the quality of manufactured products and the process capability. Currently, the dimensional …
the quality of manufactured products and the process capability. Currently, the dimensional …
Using design of experiments to guide genetic optimization of engineered metabolic pathways
S Moon, A Saboe, MJ Smanski - Journal of Industrial …, 2024 - academic.oup.com
Abstract Design of experiments (DoE) is a term used to describe the application of statistical
approaches to interrogate the impact of many variables on the performance of a multivariate …
approaches to interrogate the impact of many variables on the performance of a multivariate …
Investigation on the tribological behavior and wear mechanism of parts processed by fused deposition additive manufacturing process
Fused deposition modeling (FDM) is a process for producing three dimensional products by
layer by layer deposition directly from a digital file, becoming, more exciting among …
layer by layer deposition directly from a digital file, becoming, more exciting among …
Parametric optimization of FDM process for PA12-CF parts using integrated response surface methodology, Grey relational analysis, and grey wolf optimization
Efficiently managing multiple process parameters is critical for achieving optimal
performance in additive manufacturing. This study investigates the relationship between …
performance in additive manufacturing. This study investigates the relationship between …
Comparative study of I-optimal design and definitive screening design for develo** prediction models and optimization of average surface roughness of PLA printed …
In fused deposition modeling (FDM), the prediction and optimization of surface roughness
distribution by varying the process parameters of the printing is required during the process …
distribution by varying the process parameters of the printing is required during the process …
Definitive screening design for mechanical properties enhancement in extrusion-based additive manufacturing of carbon fiber-reinforced PLA composite
M Abas, T Habib, I Khan, S Noor - Progress in Additive Manufacturing, 2025 - Springer
In the realm of material extrusion additive manufacturing, fused deposition modeling
(FDM)/fused filament fabrication (FFF) has gained widespread recognition for its cost …
(FDM)/fused filament fabrication (FFF) has gained widespread recognition for its cost …
Impact of processing parameters on tensile strength, in-process crystallinity and mesostructure in FDM-fabricated PLA specimens
Purpose This study aims to investigate the impact of layer thickness, extrusion temperature,
extrusion speed and build plate temperature on the tensile strength, crystallinity achieved …
extrusion speed and build plate temperature on the tensile strength, crystallinity achieved …
Bioconversion of cellulose into bisabolene using Ruminococcus flavefaciens and Rhodosporidium toruloides
In this study, organic acids were demonstrated as a promising carbon source for bisabolene
production by the non-conventional yeast, Rhodosporidium toruloides, at microscale with a …
production by the non-conventional yeast, Rhodosporidium toruloides, at microscale with a …