Immunity to fungal infections
L Romani - Nature Reviews Immunology, 2011 - nature.com
Fungal diseases represent an important paradigm in immunology, as they can result from
either a lack of recognition by the immune system or overactivation of the inflammatory …
either a lack of recognition by the immune system or overactivation of the inflammatory …
Race and ethnicity: Risk factors for fungal infections?
Racial and ethnic identities, largely understood as social rather than biologic constructs,
may impact risk for acquiring infectious diseases, including fungal infections. Risk factors …
may impact risk for acquiring infectious diseases, including fungal infections. Risk factors …
Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient-and donor …
The C-type lectin receptor Dectin-1 plays a pivotal role in antifungal immunity. In this study,
the recently characterized human DECTIN1 Y238X early stop codon polymorphism leading …
the recently characterized human DECTIN1 Y238X early stop codon polymorphism leading …
Important aspects of Toll-like receptors, ligands and their signaling pathways
ZL Chang - Inflammation research, 2010 - Springer
Due to the rapid increase of new information on the multiple roles of Toll-like receptors
(TLRs), this paper reviews several main properties of TLRs and their ligands and signaling …
(TLRs), this paper reviews several main properties of TLRs and their ligands and signaling …
Epidemiology and treatment approaches in management of invasive fungal infections
J Kriengkauykiat, JI Ito, SS Dadwal - Clinical epidemiology, 2011 - Taylor & Francis
Over the past 20 years, the number of invasive fungal infections has continued to persist,
due primarily to the increased numbers of patients subjected to severe immunosuppression …
due primarily to the increased numbers of patients subjected to severe immunosuppression …
TLR3 essentially promotes protective class I–restricted memory CD8+ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients
Aspergillus fumigatus is a model fungal pathogen and a common cause of severe infections
and diseases. CD8+ T cells are present in the human and murine T-cell repertoire to the …
and diseases. CD8+ T cells are present in the human and murine T-cell repertoire to the …
Invasive fungal disease and cytomegalovirus infection: is there an association?
CMV infection is associated with increased risk of IFD in posttransplant recipients because
of a number of overlap** and virus-specific risk factors. Better understanding of how CMV …
of a number of overlap** and virus-specific risk factors. Better understanding of how CMV …
Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility
M Noreen, M Arshad - Immunologic Research, 2015 - Springer
Toll like receptors (TLRs) play a crucial role in regulation of innate as well as adaptive
immunity. TLRs recognize a distinct but limited repertoire of conserved microbial products …
immunity. TLRs recognize a distinct but limited repertoire of conserved microbial products …
Human NK cells and herpesviruses: mechanisms of recognition, response and adaptation
NK cells contribute to early defenses against viruses through their inborn abilities that
include sensing of PAMPs and inflammatory signals such as cytokines or chemokines …
include sensing of PAMPs and inflammatory signals such as cytokines or chemokines …
The Y238X stop codon polymorphism in the human β-glucan receptor dectin-1 and susceptibility to invasive aspergillosis
LYA Chai, MGJ de Boer… - Journal of Infectious …, 2011 - academic.oup.com
Background. Dectin-1 is the major receptor for fungal β-glucans on myeloid cells. We
investigated whether defective Dectin-1 receptor function, because of the early stop codon …
investigated whether defective Dectin-1 receptor function, because of the early stop codon …