Multiple forms and functions of premature termination by RNA polymerase II
DL Bentley - Journal of Molecular Biology, 2024 - Elsevier
Eukaryotic genomes are widely transcribed by RNA polymerase II (pol II) both within genes
and in intergenic regions. POL II elongation complexes comprising the polymerase, the DNA …
and in intergenic regions. POL II elongation complexes comprising the polymerase, the DNA …
The Integrator complex: an emerging complex structure involved in the regulation of gene expression by targeting RNA polymerase II
T Li, F Zeng, Y Li, H Li, J Wu - Functional & Integrative Genomics, 2024 - Springer
The Integrator complex is a multisubunit complex that participates in the processing of small
nuclear RNA molecules in eukaryotic cells by cleaving the 3'end. In protein-coding genes …
nuclear RNA molecules in eukaryotic cells by cleaving the 3'end. In protein-coding genes …
Assembly mechanism of Integrator's RNA cleavage module
K Sabath, C Qiu, S Jonas - Molecular Cell, 2024 - cell.com
The modular Integrator complex is a transcription regulator that is essential for embryonic
development. It attenuates coding gene expression via premature transcription termination …
development. It attenuates coding gene expression via premature transcription termination …