Current state of potential mechanisms supporting low intensity focused ultrasound for neuromodulation

J Dell'Italia, JL Sanguinetti, MM Monti… - Frontiers in human …, 2022 - frontiersin.org
Low intensity focused ultrasound (LIFU) has been gaining traction as a non-invasive
neuromodulation technology due to its superior spatial specificity relative to transcranial …

Low intensity focused ultrasound: a new prospect for the treatment of Parkinson's disease

YX Zhong, JC Liao, X Liu, H Tian, LR Deng… - Annals of …, 2023 - Taylor & Francis
Background: As a chronic and progressive neurodegenerative disease, Parkinson's disease
(PD) still lacks effective and safe targeted drug therapy. Low-intensity focused ultrasound …

[HTML][HTML] Effects of different sonication parameters of theta burst transcranial ultrasound stimulation on human motor cortex

K Zeng, Z Li, X **a, Z Wang, G Darmani, X Li, R Chen - Brain Stimulation, 2024 - Elsevier
Abstract Background Theta burst TUS (tbTUS) can induce increased cortical excitability in
human, but how different sonication parameters influence the effects are still unknown …

The effectiveness and safety of low-intensity transcranial ultrasound stimulation: A systematic review of human and animal studies

PP Qin, M **, AW **a, AS Li, TT Lin, Y Liu… - Neuroscience & …, 2024 - Elsevier
Low-intensity transcranial ultrasound stimulation (LITUS) is a novel non-invasive
neuromodulation technique. We conducted a systematic review to evaluate current evidence …

[HTML][HTML] The relationship between parameters and effects in transcranial ultrasonic stimulation.

T Nandi, BR Kop, KB Pauly, CJ Stagg, L Verhagen - Brain Stimulation, 2024 - Elsevier
Transcranial ultrasonic stimulation (TUS) is rapidly gaining traction for non-invasive human
neuromodulation, with a pressing need to establish protocols that maximise …

[HTML][HTML] Modulation effects of low-intensity transcranial ultrasound stimulation on the neuronal firing activity and synaptic plasticity of mice

Z Zhao, H Ji, C Zhang, J Pei, X Zhang, Y Yuan - NeuroImage, 2023 - Elsevier
Low-intensity transcranial ultrasound stimulation (TUS) has been effective in modulating
several neurological and psychiatric disorders. However, how TUS modulates neuronal …

Weak ultrasound contributes to neuromodulatory effects in the rat motor cortex

PC Chu, CS Huang, PK Chang, RS Chen… - International Journal of …, 2023 - mdpi.com
Transcranial focused ultrasound (tFUS) is a novel neuromodulating technique. It has been
demonstrated that the neuromodulatory effects can be induced by weak ultrasound …

Time–frequency cross-coupling between cortical low-frequency neuronal calcium oscillations and blood oxygen metabolism evoked by ultrasound stimulation

Z Su, J Yan, H Ji, M Liu, X Zhang, X Li, Y Yuan - Cerebral Cortex, 2023 - academic.oup.com
Low-intensity transcranial ultrasound stimulation (TUS) can modulate the coupling of high-
frequency (160–200 Hz) neural oscillations and cerebral blood oxygen metabolism (BOM); …

L-type calcium channel modulates low-intensity pulsed ultrasound-induced excitation in cultured hippocampal neurons

WY Fan, YM Chen, YF Wang, YQ Wang, JQ Hu… - Neuroscience …, 2024 - Springer
As a noninvasive technique, ultrasound stimulation is known to modulate neuronal activity
both in vitro and in vivo. The latest explanation of this phenomenon is that the acoustic wave …