Therapeutic advances in multiple sclerosis
Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system that
causes significant disability and healthcare burden. The treatment of MS has evolved over …
causes significant disability and healthcare burden. The treatment of MS has evolved over …
Ocrelizumab: a review in multiple sclerosis
YN Lamb - Drugs, 2022 - Springer
Ocrelizumab (Ocrevus®) is an intravenously administered, humanized anti-CD20
monoclonal antibody approved for the treatment of adults with relapsing forms of multiple …
monoclonal antibody approved for the treatment of adults with relapsing forms of multiple …
Disease‐modifying therapies and coronavirus disease 2019 severity in multiple sclerosis
Objective This study was undertaken to assess the impact of immunosuppressive and
immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in …
immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in …
[HTML][HTML] Practical guidance for the diagnosis and management of secondary hypogammaglobulinemia: a work group report of the AAAAI primary immunodeficiency …
IM Otani, HK Lehman, AM Jongco, LR Tsao… - Journal of Allergy and …, 2022 - Elsevier
Secondary hypogammaglobulinemia (SHG) is characterized by reduced immunoglobulin
levels due to acquired causes of decreased antibody production or increased antibody loss …
levels due to acquired causes of decreased antibody production or increased antibody loss …
COVID-19 vaccine-readiness for anti-CD20-depleting therapy in autoimmune diseases
Although most autoimmune diseases are considered to be CD4 T cell-or antibody-mediated,
many respond to CD20-depleting antibodies that have limited influence on CD4 and plasma …
many respond to CD20-depleting antibodies that have limited influence on CD4 and plasma …
Anti-CD20 therapies for multiple sclerosis: current status and future perspectives
Multiple sclerosis (MS) is a chronic inflammatory, demyelinating and neurodegenerative
disease affecting the central nervous system (CNS), often characterized by the accumulation …
disease affecting the central nervous system (CNS), often characterized by the accumulation …
Ocrelizumab extended interval dosing in multiple sclerosis in times of COVID-19
L Rolfes, M Pawlitzki, S Pfeuffer, C Nelke… - Neurology …, 2021 - neurology.org
Objective To evaluate the clinical consequences of extended interval dosing (EID) of
ocrelizumab in relapsing-remitting multiple sclerosis (RRMS) during the coronavirus disease …
ocrelizumab in relapsing-remitting multiple sclerosis (RRMS) during the coronavirus disease …
Drugs targeting CD20 in multiple sclerosis: pharmacology, efficacy, safety, and tolerability
Currently, there are four monoclonal antibodies (mAbs) that target the cluster of
differentiation (CD) 20 receptor available to treat multiple sclerosis (MS): rituximab …
differentiation (CD) 20 receptor available to treat multiple sclerosis (MS): rituximab …
Safety experience with continued exposure to ofatumumab in patients with relapsing forms of multiple sclerosis for up to 3.5 years
Background: Ofatumumab is approved for the treatment of relapsing multiple sclerosis
(RMS). Ongoing safety reporting is crucial to understand its long-term benefit–risk profile …
(RMS). Ongoing safety reporting is crucial to understand its long-term benefit–risk profile …
Safety and efficacy of COVID-19 vaccines in multiple sclerosis patients
H Kelly, B Sokola, H Abboud - Journal of Neuroimmunology, 2021 - Elsevier
COVID-19 vaccination is recommended for multiple sclerosis patients. Disease-modifying
therapies can influence the safety and efficacy of COVID-19 vaccines. RNA, DNA, protein …
therapies can influence the safety and efficacy of COVID-19 vaccines. RNA, DNA, protein …