Achieving a high cell density of animal cells is a prerequisite for different medical
applications such as cell therapy, tissue engineering, and vaccine production. Microcarrier …

For several decades microparticles have been exclusively and extensively explored as
spherical drug delivery vehicles and large-scale cell expansion carriers. More recently …

To harness the full potential of human pluripotent stem cells (hPSCs) we combined
instrumented stirred tank bioreactor (STBR) technology with the power of in silico process …

Manifestations of cardiovascular diseases (CVDs) in a patient or a population differ based
on inherent biological makeup, lifestyle, and exposure to environmental risk factors. These …

Cellular therapies based on human pluripotent stem cells (hPSCs) offer considerable
promise for treating numerous diseases including diabetes and end stage liver failure. Stem …

The development of bioprocesses capable of producing large numbers of human induced
pluripotent stem cells (hiPSC) in a robust and safe manner is critical for the application of …

To fully utilize the potential of human induced pluripotent stem cells (hiPSCs) for allogeneic
stem cell–based therapies, efficient and scalable expansion procedures must be developed …

This report summarizes key issues contributing to the cost of preparing human pluripotent
stem cell lines for use in cell therapy manufacturing based on discussion between stem cell …

Recently, stem cell-based therapies have been proposed as an alternative for the treatment
of many diseases. Stem cells (SCs) are well known for their capacity to preserve themselves …

Human induced pluripotent stem cells (hiPSCs) are manufactured as advanced therapy
medicinal products for tissue replacement applications. With this aim, the feasibility of hiPSC …