This new book, The Epilepsies, details the most recent advances in epileptic seizures,
epileptic syndromes and their management. It is based on the International League Against …

Although the cellular mechanisms of pharmacological actions of gabapentin (Neurontin®)
remain incompletely described, several hypotheses have been proposed. It is possible that …

Background Carbamazepine is widely accepted as a drug of first choice for patients with
partial onset seizures. Several newer drugs possess efficacy against these seizure types but …

Objective: To assess the evidence demonstrating efficacy, tolerability, and safety of seven
new antiepileptic drugs (AEDs)(gabapentin, lamotrigine, topiramate, tiagabine …

Purpose: To evaluate the efficacy and safety of lacosamide when added to 1 or 2
antiepileptic drugs (AEDs) in adults with uncontrolled partial‐onset seizures, and assess …

Few epilepsy surgery outcome data are available from series of pediatric patients. We
studied seizure outcome in 136 pediatric patients who had surgery for intractable epilepsy at …

Purpose: To evaluate the efficacy and safety of lacosamide (200 and 400 mg/day) when
added to one to three concomitant antiepileptic drugs (AEDs) in patients with uncontrolled …

With the introduction of several new antiepileptic drugs into clinical practice, renewed
attention has been focussed on treatment-emergent adverse effects, including mood …

Amyotrophic lateral sclerosis (ALS) is an age-related neurodegenerative disorder that is
believed to have complex genetic and environmental influences in the pathogenesis, but …

A history of depression or depressive symptomatology has been reported in up to two‐thirds
of patients with medically intractable epilepsy, whereas community studies have …