Bioactive compounds of the Mediterranean diet as nutritional support to fight neurodegenerative disease

GA Franco, L Interdonato, M Cordaro… - International journal of …, 2023 - mdpi.com
Neurodegenerative disorders are a widespread cause of morbidity and mortality worldwide,
characterized by neuroinflammation, oxidative stress, and neuronal depletion. They include …

Antidepressant Potential of Quercetin and its Glycoside Derivatives: A Comprehensive Review and Update

S Chen, Y Tang, Y Gao, K Nie, H Wang, H Su… - Frontiers in …, 2022 - frontiersin.org
Depression is a global health problem with growing prevalence rates and serious impacts
on the daily life of patients. However, the side effects of currently used antidepressants …

[HTML][HTML] Cashew (Anacardium occidentale L.) Nuts Counteract Oxidative Stress and Inflammation in an Acute Experimental Model of Carrageenan-Induced Paw …

M Cordaro, R Siracusa, R Fusco, R D'Amico… - Antioxidants, 2020 - mdpi.com
Background: Anacardium occidentale L. is a medicinal plant with powerful anti-oxidative and
anti-inflammatory properties. Acute inflammatory events cause tissue alterations, decrease …

The Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale L. Cashew Nuts in a Mouse Model of Colitis

R Siracusa, R Fusco, AF Peritore, M Cordaro… - Nutrients, 2020 - mdpi.com
Background: Anacardium occidentale L. is a tropical plant used for the treatment of
inflammatory diseases. The goal of the present work was to investigate the anti-inflammatory …

Quercetin prevents osteoarthritis progression possibly via regulation of local and systemic inflammatory cascades

H Wang, Y Yan, JL Pathak, W Hong… - Journal of cellular …, 2023 - Wiley Online Library
Due to the lack of effective treatments, osteoarthritis (OA) remains a challenge for clinicians.
Quercetin, a bioflavonoid, has shown potent anti‐inflammatory effects. However, its effect on …

Quercetin alleviates neuropathic pain in the rat CCI model by mediating AMPK/MAPK pathway

G Ye, C Lin, Y Zhang, Z Ma, Y Chen, L Kong… - Journal of Pain …, 2021 - Taylor & Francis
Context Quercetin (que) is one abundant flavonol with a variety of biological activities.
Previous studies have shown quercetin can reduce neuropathic pain in rats with chronic …

[HTML][HTML] ALIAmides update: palmitoylethanolamide and its formulations on management of peripheral neuropathic pain

R D'Amico, D Impellizzeri, S Cuzzocrea… - International Journal of …, 2020 - mdpi.com
Neuropathic pain results from lesions or diseases of the somatosensory nervous system and
it remains largely difficult to treat. Peripheral neuropathic pain originates from injury to the …

Natural compounds: potential therapeutics for the inhibition of cartilage matrix degradation in osteoarthritis

OS Ashruf, MY Ansari - Life, 2022 - mdpi.com
Osteoarthritis (OA) is the most common degenerative joint disease characterized by
enzymatic degradation of the cartilage extracellular matrix (ECM) causing joint pain and …

[HTML][HTML] Discovering the effects of fisetin on NF-κB/NLRP-3/NRF-2 molecular pathways in a mouse model of vascular dementia induced by repeated bilateral carotid …

M Cordaro, R D'Amico, R Fusco, AF Peritore… - Biomedicines, 2022 - mdpi.com
Vascular dementia (VaD) is the second leading cause of dementia. The majority of VaD
patients have cognitive abnormalities, which are caused by cerebral hypoperfusion-induced …

[HTML][HTML] The Role of Cashew (Anacardium occidentale L.) Nuts on an Experimental Model of Painful Degenerative Joint Disease

R Fusco, R Siracusa, AF Peritore, E Gugliandolo… - Antioxidants, 2020 - mdpi.com
Osteoarthritis is a progressive joint disease characterized by the activation of different
molecular mediators, including proinflammatory cytokines, reactive oxygen species …