The preventive treatment of latent tuberculosis infection (LTBI) is of great importance for the
elimination and control of tuberculosis (TB) worldwide, but existing screening methods for …

Development of idiosyncratic hepatotoxicity is an intricate process involving both concurrent
as well as sequential events determining the direction of the pathways, degree of liver injury …

Comprehensive guidelines for treatment of latent tuberculosis infection (LTBI) among
persons living in the United States were last published in 2000 (American Thoracic Society …

Executive summary Tuberculosis (TB) strains with drug resistance (DR-TB) are more difficult
to treat than drug-susceptible ones, and threaten global progress towards the targets set by …

Background A 9-month regimen of isoniazid can prevent active tuberculosis in persons with
latent tuberculosis infection. However, the regimen has been associated with poor …

The WHO consolidated guidelines on tuberculosis: tuberculosis preventive treatment
provides a comprehensive set of recommendations for programmatic management of …

Background: Treatment of latent tuberculosis infection (LTBI) is an important component of
tuberculosis (TB) control, and this study updates a previous network meta-analysis of the …

Drug-induced liver injury (DILI) is a problem of increasing significance, but has been a long-
standing concern in the treatment of tuberculosis (TB) infection. The liver has a central role …

Background The treatment of latent infection with Mycobacterium tuberculosis is important in
children because of their vulnerability to life-threatening forms of tuberculosis disease. The …

This article reviews recommended strategies for screening and treatment of latent
tuberculosis in the United States, with attention to the role of interferon-γ–release assays in …