As invaluable as the standard 2-dimensional (2D) monolayer in vitro cell culture system has
been, there is increasing evidence that 3-dimensional (3D) non-adherent conditions are …

The homeobox domain transcription factor NANOG, a key regulator of embryonic
development and cellular reprogramming, has been reported to be broadly expressed in …

Mesenchymal stem cells (MSCs) possess potent immunomodulatory activity and have been
extensively investigated for their therapeutic potential in treating inflammatory disorders …

Mesenchymal stem cell transplantation (MSCT) has been used to treat human diseases, but
the detailed mechanisms underlying its success are not fully understood. Here we show that …

Mammary stem/progenitor cells (MaSCs) maintain self-renewal of the mammary epithelium
during puberty and pregnancy. DNA methylation provides a potential epigenetic mechanism …

Pro-fibrotic microenvironments of scars and tumors characterized by increased stiffness
stimulate mesenchymal stromal cells (MSCs) to express α-smooth muscle actin (α-SMA). We …

A number of molecular pathways play key roles in transmitting information in addition to the
genomic sequence—epigenetic information—from one generation to the next. However, so …

Mesenchymal stem cells (MSCs) are attractive candidates for clinical repair or regeneration
of damaged tissues. Oct4 and Sox2, which are essential transcription factors for pluripotency …

dimensional (3D) bioprinting technology provides promising strategy in the fabrication of
artificial tissues and organs. As the fundamental element in bioprinting process, preparation …

Mesenchymal stem cells (MSC) have been considered the promising candidates for the
regenerative and personalized medicine due to their self-renewal potential, multilineage …