Contingent upon concentration, reactive oxygen species (ROS) influence cancer evolution
in apparently contradictory ways, either initiating/stimulating tumorigenesis and supporting …

Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous
ROS production in normal cells is controlled by the appropriate regulation between the silver …

The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …

Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

Vitiligo is a common chronic acquired pigmentation disorder characterized by loss of
pigmentation. Among various hypotheses proposed for the pathogenesis of vitiligo, oxidative …

The rapid increase in both the lifespan and proportion of older adults is accompanied by the
unprecedented rise in age-associated chronic diseases, including sarcopenia and obesity …

The TP53 tumor suppressor gene is the most frequently altered gene in tumors and an
increasing number of studies highlight that mutant p53 proteins can acquire oncogenic …

Accumulating evidence shows that elevated levels of reactive oxygen species (ROS) are
associated with cancer initiation, growth, and response to therapies. As concentrations …

Coptisine is isoquinoline alkaloid derived from Coptidis Rhizoma and is known to have
potential anti-cancer activity toward various carcinomas. Targeting autophagy is one of the …

Autophagy and the lysosomal system, together referred to as the autophagolysosomal
system, is a cellular quality control network which maintains cellular health and homeostasis …