Papillary and follicular thyroid carcinoma

MJ Schlumberger - New england journal of medicine, 1998 - Mass Medical Soc
Papillary and follicular (differentiated) thyroid carcinomas are among the most curable
cancers. However, some patients are at high risk for recurrent disease or even death. Most …

Pathogenetic mechanisms in thyroid follicular-cell neoplasia

T Kondo, S Ezzat, SL Asa - Nature Reviews Cancer, 2006 - nature.com
Thyroid cancer is one of the few malignancies that are increasing in incidence. Recent
advances have improved our understanding of its pathogenesis; these include the …

Thyroid cancer in the pediatric population

VA Paulson, ER Rudzinski, DS Hawkins - Genes, 2019 - mdpi.com
Thyroid cancer is rare in the pediatric population, but thyroid carcinomas occurring in
children carry a unique set of clinical, pathologic, and molecular characteristics. In …

RET/PTC rearrangement in thyroid tumors

YE Nikiforov - Endocrine pathology, 2002 - Springer
Rearrangement of the RET gene, also known as RET/PTC rearrangement, is the most
common genetic alteration identified to date in thyroid papillary carcinomas. The prevalence …

NTRK fusion oncogenes in pediatric papillary thyroid carcinoma in northeast United States

ML Prasad, M Vyas, MJ Horne, RK Virk, R Morotti… - Cancer, 2016 - Wiley Online Library
BACKGROUND An increase in thyroid cancers, predominantly papillary thyroid carcinoma
(PTC), has been recently reported in children. METHODS The histopathology of 28 …

Pattern of Radiation-induced RET and NTRK1 Rearrangements in 191 Post-Chernobyl Papillary Thyroid Carcinomas: Biological, Phenotypic, and Clinical …

HM Rabes, EP Demidchik, JD Sidorow… - Clinical Cancer …, 2000 - AACR
Molecular genetic aberrations and the related phenotypes were investigated in 191 papillary
thyroid carcinomas (PTCs) from patients exposed at young age to radioiodine released from …

The treatment of differentiated thyroid cancer in children: emphasis on surgical approach and radioactive iodine therapy

SA Rivkees, EL Mazzaferri, FA Verburg… - Endocrine …, 2011 - academic.oup.com
Pediatric thyroid cancer is a rare disease with an excellent prognosis. Compared with adults,
epithelial-derived differentiated thyroid cancer (DTC), which includes papillary and follicular …

Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis

AC Porter, RR Vaillancourt - Oncogene, 1998 - nature.com
Oncogenesis is a complicated process involving signal transduction pathways that mediate
many different physiological events. Typically, oncogenes cause unregulated cell growth …

Current knowledge about the impact of microgravity on gene regulation

TJ Corydon, H Schulz, P Richter, SM Strauch… - Cells, 2023 - mdpi.com
Microgravity (µ g) has a massive impact on the health of space explorers. Microgravity
changes the proliferation, differentiation, and growth of cells. As crewed spaceflights into …

RET/PTC rearrangements in thyroid nodules: studies in irradiated and not irradiated, malignant and benign thyroid lesions in children and adults

R Elisei, C Romei, T Vorontsova, B Cosci… - The Journal of …, 2001 - academic.oup.com
Rearrangements of the RET proto-oncogene may occur in both naturally occurring and
radiation-induced papillary thyroid carcinomas. Conflicting results on the frequency and type …