Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms
The heterotrimeric RNA-dependent RNA polymerase of influenza viruses catalyzes RNA
replication and transcription activities in infected cell nuclei. The nucleotide polymerization …
replication and transcription activities in infected cell nuclei. The nucleotide polymerization …
CagA-mediated pathogenesis of Helicobacter pylori
A Tohidpour - Microbial pathogenesis, 2016 - Elsevier
Helicobacter pylori has been described as the main etiologic agent of gastric cancer,
causing a considerable rate of mortality and morbidity in human population across the world …
causing a considerable rate of mortality and morbidity in human population across the world …
Helicobacter pylori Type IV Secretion Apparatus Exploits β1 Integrin in a Novel RGD-Independent Manner
LF Jiménez-Soto, S Kutter, X Sewald, C Ertl… - PLoS …, 2009 - journals.plos.org
Translocation of the Helicobacter pylori (Hp) cytotoxin-associated gene A (CagA) effector
protein via the cag-Type IV Secretion System (T4SS) into host cells is a major risk factor for …
protein via the cag-Type IV Secretion System (T4SS) into host cells is a major risk factor for …
Tertiary structure-function analysis reveals the pathogenic signaling potentiation mechanism of Helicobacter pylori oncogenic effector CagA
T Hayashi, M Senda, H Morohashi, H Higashi… - Cell host & …, 2012 - cell.com
The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence
determinant and critical for gastric carcinogenesis. Upon delivery into gastric epithelial cells …
determinant and critical for gastric carcinogenesis. Upon delivery into gastric epithelial cells …
Structural insights into Helicobacter pylori oncoprotein CagA interaction with β1 integrin
B Kaplan-Türköz, LF Jiménez-Soto… - Proceedings of the …, 2012 - National Acad Sciences
Infection with the gastric pathogen Helicobacter pylori is a risk factor for the development of
gastric cancer. Pathogenic strains of H. pylori carry a type IV secretion system (T4SS) …
gastric cancer. Pathogenic strains of H. pylori carry a type IV secretion system (T4SS) …
Architecture of the Helicobacter pylori Cag‐type IV secretion system
Type IV secretion systems (T4SS) are macromolecular assemblies used by bacteria to
transport material across their membranes. T4SS are generally composed of a set of twelve …
transport material across their membranes. T4SS are generally composed of a set of twelve …
Towards an atomic resolution understanding of the influenza virus replication machinery
The influenza polymerase transcribes and replicates the viral RNA genome within the
context of a ribonucleoprotein complex that has been hitherto remarkably intractable to …
context of a ribonucleoprotein complex that has been hitherto remarkably intractable to …
Structural-dynamic insights into the H. pylori cytotoxin-associated gene A (CagA) and its abrogation to interact with the tumor suppressor protein ASPP2 using decoy …
Helicobacter pylori (H. pylori) is one of the most extensively studied Gram-negative bacteria
due to its implication in gastric cancer. The oncogenicity of H. pylori is associated with …
due to its implication in gastric cancer. The oncogenicity of H. pylori is associated with …
When is Helicobacter pylori acquired in populations in develo** countries? A birth-cohort study in Bangladeshi children
S Kienesberger, GI Perez-Perez, AZ Olivares… - Gut …, 2018 - Taylor & Francis
Helicobacter pylori colonization is prevalent throughout the world, and is predominantly
acquired during childhood. In develo** countries,> 70% of adult populations are …
acquired during childhood. In develo** countries,> 70% of adult populations are …
ESPRIT: an automated, library-based method for map** and soluble expression of protein domains from challenging targets
H Yumerefendi, F Tarendeau, PJ Mas… - Journal of structural biology, 2010 - Elsevier
Expression of sufficient quantities of soluble protein for structural biology and other
applications is often a very difficult task, especially when multimilligram quantities are …
applications is often a very difficult task, especially when multimilligram quantities are …