The frequently studied polysaccharide, chitosan oligosaccharide/chitooligosaccharide
(COS) is the major degradation product of chitosan/chitin via chemical hydrolysis or …

Chitosan oligosaccharide (COS) is an oligomer of β-(1➔ 4)-linked d-glucosamine. COS can
be prepared from the deacetylation and hydrolysis of chitin, which is commonly found in the …

This study presents the influence of the primary formulation parameters on the formation of
poly-DL-lactic-co-glycolic nanoparticles by the emulsification-solvent evaporation, and the …

The viscoelastic mucus secretions coating exposed organs such as the lung airways and the
female reproductive tract can trap and quickly eliminate not only foreign pathogens and …

Protein/antibody therapeutics have exhibited the advantages of high specificity and activity
even at an extremely low concentration compared to small molecule drugs. However, they …

Abstract Encapsulation in polymer NPs (NPs) is a well-recognized way to improve the oral
bioavailability of hydrophobic and hydrophilic compounds by enhancing their solubility in …

Oral administration has been the most common therapeutic regimen in various diseases
because of its high safety, convenience, lower costs, and high compliance of patients …

Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

Indocyanine green (ICG) has been used clinically and noticed as a promising candidate for
the topical melanoma photodynamic therapy (PDT). Despite its high potentials in topical …

Despite the wide range of diseases affecting the eye, ocular bioavailability remains a
challenge in ophthalmic drug delivery. Nowadays an extensive variety of polymers are being …