The impact of the gut microbiome on extra-intestinal autoimmune diseases
E Miyauchi, C Shimokawa, A Steimle… - Nature Reviews …, 2023 - nature.com
The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …
Intestinal barrier in human health and disease
The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …
protection from external factors. It consists of epithelial cells, immune cells and their …
Gut microbiota and immune system interactions
Dynamic interactions between gut microbiota and a host's innate and adaptive immune
systems are essential in maintaining intestinal homeostasis and inhibiting inflammation. Gut …
systems are essential in maintaining intestinal homeostasis and inhibiting inflammation. Gut …
Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases
The gut microbiota has a critical role in the maintenance of immune homeostasis. Alterations
in the intestinal microbiota and gut microbiota-derived metabolites have been recognized in …
in the intestinal microbiota and gut microbiota-derived metabolites have been recognized in …
The human gut microbiome–a potential controller of wellness and disease
Interest toward the human microbiome, particularly gut microbiome has flourished in recent
decades owing to the rapidly advancing sequence-based screening and humanized …
decades owing to the rapidly advancing sequence-based screening and humanized …
Causal effects of gut microbiome on systemic lupus erythematosus: a two-sample Mendelian randomization study
K **ang, P Wang, Z Xu, YQ Hu, YS He, Y Chen… - Frontiers in …, 2021 - frontiersin.org
The observational association between gut microbiome and systemic lupus erythematosus
(SLE) has been well documented. However, whether the association is causal remains …
(SLE) has been well documented. However, whether the association is causal remains …
Elucidating the role of diet in maintaining gut health to reduce the risk of obesity, cardiovascular and other age-related inflammatory diseases: Recent challenges and …
ABSTRACT A healthy balanced diet is crucial in protecting the immune system against
infections and diseases. Poor diets, such as the Western diet, contribute to the development …
infections and diseases. Poor diets, such as the Western diet, contribute to the development …
Microbial dysbiosis in the gut drives systemic autoimmune diseases
WK Mousa, F Chehadeh, S Husband - Frontiers in immunology, 2022 - frontiersin.org
Trillions of microbes survive and thrive inside the human body. These tiny creatures are
crucial to the development and maturation of our immune system and to maintain gut …
crucial to the development and maturation of our immune system and to maintain gut …
Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensal
Background/Purpose To search for a transmissible agent involved in lupus pathogenesis,
we investigated the faecal microbiota of patients with systemic lupus erythematosus (SLE) …
we investigated the faecal microbiota of patients with systemic lupus erythematosus (SLE) …
Crosstalk between gut microbiota and innate immunity and its implication in autoimmune diseases
The emerging concept of microbiota contributing to local mucosal homeostasis has fueled
investigation into its specific role in immunology. Gut microbiota is mostly responsible for …
investigation into its specific role in immunology. Gut microbiota is mostly responsible for …