Stochastic simulation software that simultaneously model genetic, population and
environmental processes can inform many topics in molecular ecology. These include …

The distribution of fitness effects (DFE) has considerable importance in population genetics.
To date, estimates of the DFE come from studies using a small number of individuals. Thus …

In this paper we describe how to efficiently record the entire genetic history of a population in
forwards-time, individual-based population genetics simulations with arbitrary breeding …

The distribution of fitness effects (DFE) of new mutations plays a fundamental role in
evolutionary genetics. However, the extent to which the DFE differs across species has yet to …

A novel approach for dissecting complex traits is to experimentally evolve laboratory
populations under a controlled environment shift, resequence the resulting populations, and …

forqs is a forward-in-time simulation of recombination, quantitative traits and selection. It was
designed to investigate haplotype patterns resulting from scenarios where substantial …

SELAM is a forward time population genetic simulation program that provides a flexible
framework for simulating admixture between any number of ancestral populations. The …

Evolutionary forces shape patterns of genetic diversity within populations and contribute to
phenotypic variation. In particular, recurrent positive selection has attracted significant …

Real or imputed high-density SNP genotypes are routinely used for genomic prediction and
genome-wide association studies. Many researchers are moving toward the use of actual or …

Amb la creixent disponibilitat de dades a escala de l'genoma per a la investigació genètica,
els genetistes de poblacions moleculars han de treballar amb models més complexos, el …